Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID24789	Ibrutinib	GSE70138	SKL	Human	24h	1.11uM	EID0061

Response Information :

Types	Number	Response transcription factors
Up-regulation	38	CD3D; NKX2-1; RNF10; BRPF1; CTR9; DEAF1; RNF141; TRIP6; EGR3; NFIB; BCL11B; PLAGL2; ZNF266; NR2C1; CHD1; LPIN2; FOXK2; ZNF652; SERTAD2; CARHSP1; ZBTB16; ID1; RREB1; ENO1; MAF; HTATIP2; ELF3; NFATC3; ZFP36L2; ZNF281; ZMYM2; CRYM; RUNX3; FLNA; CITED2; NR4A2; HOXC6; ATF5
Down-regulation	60	SAFB2; PBX1; CALR; TOX3; ZNF232; SMARCB1; GATA6; BHLHE41; TFAP2C; SOX13; TGIF2; CREM; LZTS1; ZHX2; NANOG; LOXL2; MYCL; SNAI2; TCF21; KLF4; ZNF91; WT1; RARA; ZNF124; EN1; TAF1A; CBFB; HEY2; BANP; MYCBP; SUB1; WDHD1; HOXB6; TWIST1; IRF9; SMAD3; MYCN; PURA; RBFOX2; MITF; HOXB2; LIN28A; HEY1; VPS72; SAP30; MNDA; CDK2; HHEX; MEIS2; ESR1; SOX11; ELF4; IFI16; ETS2; EMX2; HOXB7; ID4; MEIS1; MYBL1; KDM5D