Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID24714 Nvp-bgj398 GSE70138 NPC Human 24h 10uM EID0054
Types Number Response transcription factors
Up-regulation 381 HNF4G; NFATC4; ATOH1; EMX1; THRB; ACTL6B; BCL11A; FOXA2; JUP; TP73; TSHZ2; PPARA; PROP1; ZNF225; DAXX; IRF6; MED25; EHF; HNF1A; CDX1; ETV3; ZXDB; EPAS1; ASCL3; JUN; ATN1; ZNF215; ZNF33B; ELF4; ZHX2; FOXH1; PRDM9; ZNF467; CIITA; POU4F3; HESX1; ZNF471; TBX5; REL; HOXB9; BACH2; VDR; SOX14; CHD2; KLF15; ZNF816; NR5A1; ZNF235; ZNF227; RFX1; SOX12; ZNF155; SOX18; ZNF75D; TFDP3; TRPS1; TBX1; HOXB8; POU6F2; ZNF74; TULP2; ASCL2; ZNF154; ZNF274; ZNF749; ZNF343; FOXC2; FOXI1; AIRE; ZNF345; ALX4; PRDM14; LBX1; ZNF81; CDX2; TBX10; ZNF41; ZNF549; ZNF780B; RORC; ZNF407; RBPJL; VHL; MDM4; VENTX; HOXD12; GBX2; ZNF550; HSF1; HBP1; ZNF480; GRIP1; FOXE3; LZTR1; ZNF688; CALCOCO1; ZNF362; NEUROG2; ZNF701; ZNF224; ZNF391; RFXANK; PAX4; MTA2; FEZF2; ZNF141; ZNF460; PAX1; SSX7; ZNF674; SPDEF; ZNF80; SKIL; HES2; VGLL1; ZFY; TAF5L; TP63; ZNF507; MZF1; ZNF354A; SPI1; CBFA2T3; NR5A2; TCEA2; KLF1; IFNB1; ZNF623; NHLH1; ZNF223; POU2F3; ZNF331; ZNF696; HOXD9; ZNF814; POU1F1; NFKB2; GCM2; NEUROD2; SMARCB1; MYRF; CCNH; SETDB1; SPIB; NEUROD6; TULP1; TRIP11; DLX6; CARF; LHX3; ZNF214; USP21; PRDM2; GSC2; HOXB1; ZKSCAN8; KLF8; AFF4; LYL1; NFE2L3; ZKSCAN4; ZBTB3; AFF2; MLLT1; ZNF324; HMGXB3; CBX8; TEF; ZNF250; TAF4B; PPP1R13L; HOXB2; SUPT3H; LHX6; PGR; FLI1; NFE2L2; TAF1; THRA; ZNF444; FOXB1; PNRC1; TDP2; FOXD3; ZNF157; ZNF132; GATA1; HOXB5; BCL3; INSM1; AFF3; PAX5; POU4F1; ZNF778; TRIB3; SOX13; ZNF695; SP1; MAML3; HOXD1; IKZF3; TLX3; KLF3; SCRT1; HIC2; TAF6L; ZNF580; UBTF; DOT1L; ZBTB7B; ZNF264; ZBTB16; ZFHX3; ZNF835; SIX3; CSDC2; ZNF665; HIRA; ASH1L; MAK; SRY; SRCAP; HIPK3; HLX; SNAPC4; CBFA2T2; SP100; KLF9; ELF3; JAK2; WWP1; RARG; OVOL1; ZNF180; SOX1; TFAP2A; BNC1; POU4F2; NKRF; CBX4; SOX21; KDM4C; ZNF682; ZNF440; PML; PTRF; ZNF675; MED14; HOXC8; CEBPG; SIM1; HIPK2; TSC22D3; MYT1; TEAD4; ZNF787; TCEA1; FOXJ1; PAWR; CNOT3; HOXD3; JUNB; WNT4; SOX17; ZNF652; DLX5; NR2F1; ARNT2; ERF; TRIM16; MED24; ZNF239; MBD2; ZNF544; ZNF135; YEATS2; ZNF606; HDAC9; NR0B1; SNAI2; ZNF611; E2F5; ACTL6A; OVOL2; ZNF112; HDAC5; WT1; RAD21; HOXB13; AR; AES; GTF2I; GFI1B; PIAS4; ESR1; HIVEP2; PHOX2B; TFAP2C; ARID5A; WWC1; KLF13; OSR2; NPAS2; RARA; NKX3-2; ST18; BTG1; YBX3; ZNF557; AGO2; PRDM12; ZKSCAN1; INSR; HHEX; HIVEP1; CBX7; ZNF667; TRIM29; NR4A2; VPS72; TAL1; EMX2; ZBED2; ID1; EYA2; TERF2; GATA6; HDAC4; SSBP3; ZNF195; UBE2B; KLF4; ZNF573; MYBL1; RELB; IL16; ZSCAN31; ZNF394; ZNF107; POU2AF1; ZFP36L1; CALR; IRF9; ZNF266; EN1; ERG; ZNF721; BHLHE41; ARID1A; RYBP; MYCL; NCOA2; MEIS2; NR4A3; GRHL2; CTBP2; HOXB6; ELF5; BRD2; TFEC; KLF6; FOXA1; ZNF551; DLX2; ZNF512B; TOX3; PBXIP1; HMGA1; ZFP36L2; FOXN3; TBL1XR1; SSX1; CEBPD; TCF7L1; AEBP1; GATA2; LOXL2; TGIF1; TBX3; DACH1; PSIP1
Down-regulation 104 ETV1; NUP62; EZH2; HDAC2; BATF3; SUV39H1; TSC22D2; SMARCC1; FHL2; CCNA2; GABPB1; ATF1; GTF2A2; ZEB2; RBM14; HNRNPD; SMARCA4; PARP1; RHOA; RBBP4; BRCA1; MAGED1; EGR1; NEDD8; CENPF; CRY1; MED27; ETV5; FOSL1; TFDP1; LZTS1; MYCBP; BMI1; TTF1; PURA; PSMC3IP; C1QBP; TRIP6; CBFB; SETD3; RXRA; CHAF1B; VEZF1; WHSC1; SFPQ; MITF; HSF2; ING3; ID4; KDM2A; MSX1; HLTF; SALL1; RNF141; CARM1; PCGF2; MED1; CBX3; ENO1; PIR; HMGN3; MSC; TSC22D4; BRD3; FOXF1; TAF10; BRD8; RBPMS; EDF1; CARHSP1; IRX5; NR2F2; CITED2; TRIM32; ZIC1; TOX; PBX3; EED; FLNA; RBBP7; PTTG1; SAP30; BCLAF1; RNF14; WWTR1; ZNF468; AFF1; CCNC; NRIP1; BAZ1A; DMTF1; DNMT3B; HES1; FOXC1; YWHAB; SMAD6; EGR2; RBBP8; MAFB; HTATIP2; ELK3; KLF2; ZBTB38; NFATC3