Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID24567 Xmd-885 GSE70138 NPC Human 24h 10uM EID0054
Types Number Response transcription factors
Up-regulation 107 E2F2; JUN; IKBKAP; IKZF1; NFIL3; BIRC2; HBP1; GFI1; BACH2; KLF1; UBE2B; BRD4; CHD4; SOX2; TAF7L; SREBF1; RNF6; UBE2I; PAX5; IL16; PRDM4; FOXO1; PIAS1; BTAF1; FOXI1; SND1; VEZF1; PAX9; BPTF; PRDM12; ELF5; NR0B1; MYT1L; POU4F1; PBXIP1; ZKSCAN1; TCF12; PSPC1; MBD2; NFATC1; PNRC1; SERTAD2; TLE4; PGR; ARID4B; CBFA2T3; CTR9; IRF4; PRRX1; ARID5B; MYB; HOXD1; CREG1; STAT1; FOXG1; ZHX2; IFI16; TAL1; RUNX1; TOB1; BCL11A; CRYM; CREBZF; ZNF107; LYL1; INSM1; ZNF467; KLF13; RYBP; TRIM22; EPAS1; INSR; TRPS1; CUX1; HLF; WNT4; MKL2; NCOA2; ZNF160; RORA; FLI1; NFE2; E2F5; PLAGL1; BRD2; SOX11; ZNF281; HHEX; CITED2; TOX3; BTG1; OSR2; CRK; ZNF721; NFIB; ZBTB16; MYBL1; ZBED2; ZMYM2; TXNIP; ARNT2; ELK3; TBX3; KLF2; TRIB3; POU2AF1; BASP1
Down-regulation 80 ATF1; FOSL1; NUP62; FHL2; PCBD1; ERBB2; GABPB1; ZNF232; HNRNPD; PCGF2; ZNF552; ZNF32; ELF4; RXRA; HMGB2; BATF3; FOXM1; HMGXB4; TP53; BRCA1; IRF6; GTF2IRD1; RBFOX2; AHR; PPP1R13L; TWIST1; BNC2; NANOG; TEAD4; MEIS1; EHMT2; MYCN; TRIP6; ING3; NAB1; TEAD1; DEK; ISL1; CUX2; CTBP2; TULP3; MSC; NR2F1; LIN28A; TGFB1I1; PHF1; CERS6; PSMC3IP; ZNF587; TOX; PIR; ETS2; EGR2; DNMT3B; ZNF331; HEY1; PAX6; PBX3; GATA6; CALR; WWTR1; CNOT3; CTNNB1; CD3D; SALL2; AFF1; ASCL1; PEG3; PDLIM1; BHLHE41; PTTG1; ZIC1; HTATIP2; MECOM; ZFP36L1; ATF3; MTA1; PSIP1; NFATC3; RELB