Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID24518	Motesanib	GSE70138	NPC	Human	24h	0.37uM	EID0053

Response Information :

Types	Number	Response transcription factors
Up-regulation	52	TBPL1; SUV39H1; RNF6; SUB1; ZBTB16; EN1; PURA; HDAC1; RBBP7; KAT2B; VDR; CNOT2; SSX1; NR1H2; SSBP3; STAT4; CDK8; TSC22D3; SATB2; ZNF281; GATAD2A; ZNF211; HDAC9; EYA2; SOHLH2; OLIG2; ZNF593; ETV5; ZNF432; ZNF580; KLF13; DLX5; SP110; YWHAB; PAX6; FOXF2; BCL6; GTF3A; MNAT1; NEUROD1; BCL3; SAP30; HOXC10; TRIM22; ELK3; TSC22D1; FOSB; HEY1; HOXC6; WWTR1; MAFB; CITED2
Down-regulation	60	ERBB2; ZNF292; MKL2; ZNF160; HMG20B; GTF2IRD1; NRIP1; SMAD4; BASP1; ZNF611; IRF5; PHF20; ZNF721; ZNF652; VEZF1; FOXN3; NFE2L1; ZNF117; REL; CBFA2T3; SFPQ; MEIS2; TXNIP; ST18; CUX2; KLF5; TULP4; COPS2; DEK; ZNF430; ZNF91; NR2F2; HHEX; ZKSCAN1; TEAD1; INSM1; CTBP2; ZNF44; SMAD1; YAP1; KLF10; TOX3; TWIST1; NR4A3; NR4A2; TRIM29; TCF4; ZNF423; ZBTB20; NR3C2; JUP; PDLIM1; TLE4; PBX3; SOX11; ID4; ERBB4; FLNA; PSIP1; NFATC3