Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID24395 Idelalisib GSE70138 NPC Human 24h 1.11uM EID0052
Types Number Response transcription factors
Up-regulation 42 EMX2; PCBD1; BCL11B; TBX19; MYC; CEBPD; IRF9; TFEC; TRIP6; STAT4; ZSCAN31; MEOX2; HLX; MSX1; JUNB; SOX17; NR0B1; CDK7; TRIM16; PBXIP1; SSX1; SMAD1; CBX7; CD3D; TLE2; ID4; IRF6; HOXB2; SUB1; FOXG1; MITF; PBX1; TP63; YBX3; RUNX3; IKBKAP; ZNF91; SOX9; CEBPB; FLNA; LEF1; PSIP1
Down-regulation 46 USP22; DMTF1; SMARCC1; RB1; TFDP1; CCNH; EDF1; CNBP; BRCA1; CHD7; MYBL2; MTF2; PBX3; TGIF2; RBM39; VEZF1; SFPQ; LOXL2; ATF3; MYB; DACH1; IRX5; FUBP1; RBBP8; ZNF721; TOX3; ZNF160; BBX; HMG20B; ZBTB1; FOXF1; TOB1; ID1; INSM1; FOSB; DLX2; ELF1; MYCN; HOXC6; NKX2-1; ZNF423; TBPL1; ID3; SNAI2; ASCL1; BHLHE41