Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID24104	Vorinostat	GSE70138	NPC.CAS9	Human	24h	10uM	EID0057

Response Information :

Types	Number	Response transcription factors
Up-regulation	110	EGR1; FOS; MYCBP; FOXO4; HMG20B; DRAP1; TBPL1; NR4A1; ATF3; TSG101; CREG1; NR4A2; CRK; CCNH; PPARD; UBE2B; PHF1; ZNF331; SIX1; NR4A3; HDAC1; ZNF394; CTR9; SND1; BCL3; FOSB; HBP1; GTF2A2; MEF2C; SETD3; PSMD9; NFIL3; TCF15; CEBPA; EGR3; DNAJC1; CREM; KLF2; AHR; ESRRA; LYL1; HTATIP2; MEF2D; RUNX3; HABP4; MNAT1; MXI1; CBX7; HLTF; JUNB; BCL10; CEBPB; PDLIM1; RUNX1; SAFB2; TSC22D4; TFAP2A; MITF; BRF2; RUVBL2; RBBP5; JUN; MLX; SP110; IRF7; CDK7; CBX4; MBD2; ETV5; DDIT3; COPS5; BRD2; SATB2; TAF10; TGFB1; ARNTL; SP100; NR3C2; SOX10; SPIB; DLX4; ZNF224; KLF10; SERTAD2; TFAP2C; ZNF593; TOB1; HMGA1; IRF8; AIP; WWC1; SMARCD3; ERBB4; VDR; EGR2; LMCD1; HHEX; SMARCA2; PTTG1; JUND; TRIP6; SSX1; BASP1; OSR2; SNAI2; MAFF; INSR; TWIST1; MNDA; PSIP1
Down-regulation	249	HMGA2; TP53; ERBB2; PCBD1; MTA1; NUP62; SMARCA4; GABPB1; ZNF84; ATF1; MYBL2; CBX5; EZH2; SMARCC1; NFYB; NCOR1; HDAC2; PATZ1; XBP1; WDHD1; WDR77; ZMYND11; MYCN; SMAD3; CCNA2; RFX7; EED; NFKBIA; PMF1; ZNF672; ZNF140; ZNF282; VPS72; TSC22D3; SOX2; ZNF43; HDGF; STAT5B; FOXM1; SETDB1; SCMH1; BCLAF1; MGA; ZNF227; ZNF529; ZNF146; ZNF22; ZNF74; ASXL1; CUX2; BRIP1; HNRNPD; NRIP1; WHSC1; HIC2; VGLL4; ZMIZ1; SIAH2; ADNP; CARHSP1; TAF9B; SALL1; TFDP1; ZNF614; ZBTB14; MEIS1; PLAGL2; ZBED1; PBX3; CTCF; SUPT7L; ETV1; SOX11; PMS1; PCGF2; RNF138; ZNF180; ZNF232; CREBZF; HMGB3; SMARCE1; USP21; RBL1; FUBP1; RAN; YAF2; MBD4; GTF2I; DEK; UBE2L3; TRRAP; NEUROD1; ZSCAN9; GCFC2; PHF2; LIN28A; IRF9; ZNF112; ZNF93; ZFP69B; ID4; GLI2; TBL1XR1; PRDM1; APEX1; SSBP3; BRD7; ZIC3; TOX3; ZFP30; PAXBP1; SFMBT1; ZNF423; TAF1D; CHD8; BCOR; SMARCA5; PCGF3; ZSCAN18; ZHX2; EHMT2; ZNF134; TRIM22; SSRP1; URI1; ZNF426; RBM39; ELF4; ZBTB1; TTF2; YEATS4; ZKSCAN8; ZNF532; HDAC9; ZBTB6; HIPK3; ZNF253; MYCL; ZFP36L1; EYA1; ZNF24; MLLT10; SMARCB1; SALL2; TRAK1; ZKSCAN7; SMAD4; ZNF443; SMARCD1; E2F5; PBX1; BAZ1A; PITX2; CIZ1; DAXX; ZNF268; CHD3; BRWD1; DEAF1; ZNF107; ILF2; HAND1; SMARCC2; BACH1; ZNF273; ZFP36L2; PSMC3IP; ZBED4; HOXC4; TCF4; ZNF432; EMX2; RBBP4; KLF7; CHD9; ZNF248; SP3; ZNF32; TCERG1; NHLH2; HIRA; ZNF711; NCOA6; BCL11A; PLAGL1; ZNF85; TLE4; ZNF266; TGIF2; NR2F6; HOXA7; NCOA2; PKNOX1; CHD7; SOX17; ZNF189; TCF7L1; ZIC1; PAX6; MDM4; DLX5; BAZ2B; HMGB2; CREB5; SLC2A4RG; VGLL1; PHIP; PHOX2B; SAP30; FOXL2; HMGN3; MED17; HOXC6; DLX2; TBL1X; ZNF195; MED24; CTBP1; SMAD1; YAP1; CTNNB1; AEBP1; ZNF117; ZBTB38; STAT6; MYB; RBPJ; ZSCAN31; FOXO1; HOXB2; MEOX1; CBFB; ARNTL2; FLNA; ZFPM2; ZEB1; ETS2; HOXB6; WT1; YBX3; MSX1; MAF; MEIS2; PIR; PEG3; ASCL1; SUV39H1; NFATC3; E2F2