Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID24095 At7867 GSE70138 NPC.CAS9 Human 24h 0.37uM EID0056
Types Number Response transcription factors
Up-regulation 207 NR3C1; IKZF1; FOS; NKX2-5; NR4A1; KLF6; PAX7; FOXJ1; VENTX; POU4F2; GON4L; HDAC11; SSX7; HOXB1; CHD2; SNAI1; EMX1; ZNF671; HCFC2; IFNB1; TBX4; EZH1; IKZF2; KMT2D; HOXC5; GATA1; ZNF507; ASXL1; HOXD13; ZBTB44; ERCC2; HNF4A; NCOA2; PROP1; POU6F1; PDX1; PRDM5; SMARCD1; HNF1A; GBX1; RFX1; HMG20A; HNF1B; MAK; PAX9; RXRG; ZNF506; HOXC11; STAT4; MEN1; HMX1; RAX; EVX1; IL16; ELF3; CIR1; ASCL3; TRIP11; RORC; ZNF154; MED25; POU2F2; EN1; CREB3L2; IRF9; FOSB; ZNF701; BNC1; PITX2; CSDC2; AIRE; ZNF493; SOX5; KDM4C; CITED1; AFF2; SMAD3; NPAT; PREB; VGLL1; ZIM2; ONECUT2; SRCAP; SHOX; FEV; FOXP3; MXD1; HOXB2; AEBP1; ESR2; LHX6; RFX7; POU2AF1; NFIX; ATF6B; HIVEP2; ZNF835; ZFP36L2; TAF4B; PAX1; HOXA3; BHLHE41; PRDM1; SSX1; KLF13; GRHL2; ZNF165; SOX21; MYF6; ZNF75D; KAT2B; TFAP2B; OVOL1; FOXK2; MEOX2; BATF; ZNF556; ZNF117; BRD8; BARX2; EYA1; NFX1; ETV5; ZNF34; MECOM; LZTS1; URI1; SP100; CAMTA2; HOXD11; IRF4; HOXA1; LPIN2; GFI1; ATF3; ELK3; MLXIPL; FOXA2; EGR4; GATA4; TBX21; MED14; CNOT6; STAT2; EYA2; PPP1R13L; IRF2; ZMYND8; MYT1L; NR0B2; OVOL2; PIAS3; NFATC1; CTBP2; ALX1; E2F2; JAK2; LEF1; ZBED2; ID4; NR0B1; PRRX1; NKX2-1; RBPMS; WNT4; PBXIP1; TERF1; SMARCA1; ZNF423; TCF7L2; NFATC3; IRF7; PKNOX2; TFCP2L1; HOXD1; SKI; HOXC10; ETV4; MEIS2; ZSCAN18; LMCD1; FOXC1; PAX5; SIM2; MBD2; TRIM22; IFI16; WWC1; HOXC6; IRF8; PEG3; ZHX2; TGFB1I1; WWTR1; TFAP2C; KLF2; RUNX3; MEIS1; AHR; TWIST1; TCF7L1; ZNF91; YBX3; NR4A2; TXNIP; KDM5D; PSIP1
Down-regulation 89 HMG20B; ENY2; EMX2; PSMC3IP; MTF2; GTF2I; COPS2; AES; ZNF32; TAF11; RNF138; ZNF24; TOX; XRCC6; ZNF184; CCNC; TAF9B; ZNF302; ZNF529; ZIC1; SAP30; ZNF263; TOX3; MYNN; CHD1; SATB2; SSBP2; MED21; RNF4; MAF; MAFB; TSC22D1; CDYL; HDAC4; CBX6; PBRM1; UBE2L3; ZNF672; ZNF146; PMS1; CBX3; FOXF1; POLR2A; THAP11; HMGB3; HHEX; ZBTB1; APEX1; ZNF267; RRN3; CTBP1; CENPB; DACH1; HBP1; SMAD4; RNF14; REPIN1; MKL2; FLNA; KLF11; TDP2; ERF; RYBP; CALR; NCOA4; RBBP4; COPS5; HEY1; PHIP; CREBL2; DMTF1; HMGN3; JUP; SUB1; ZNF43; PCGF2; SMAD6; ZFP36L1; HOXB7; SOX11; FOSL2; UBE2I; MNDA; TSC22D2; WT1; TLE4; NR2F1; BASP1; ID1