Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID24010 Kin001-244 GSE70138 NPC.CAS9 Human 24h 0.12uM EID0056
Types Number Response transcription factors
Up-regulation 92 NR1H2; RNF6; BCLAF1; NR1I2; KLF1; TSHZ2; SRCAP; PTRF; ACTL6A; SSBP3; NR1D2; MXD3; GATA1; ONECUT2; CALR; SIX6; BHLHE41; ZNF580; FOXJ1; SOX5; ZNF175; TCEB2; ZKSCAN1; KLF13; POU4F1; KDM5A; CEBPE; RXRG; PAWR; MSC; YWHAB; ETV5; NFE2; IFI16; CCNT1; TMF1; ZNF124; MYB; E2F2; WNT4; HOXB7; EGR4; BAZ1A; LZTS1; FOXF2; BBX; HDAC7; BAZ2A; BCL11A; VDR; SMAD5; ZNF394; PSMC3; MITF; TCF15; IRF4; KAT2B; PBXIP1; HOXB2; NKX2-1; EYA2; MAZ; MXI1; TFCP2L1; AEBP1; NFATC3; SOX10; ASH2L; HMGB1; ZBED2; TFAP2A; ZBTB20; PKNOX2; RUVBL2; SMAD1; TERF1; MLXIP; LIN28A; TBL1XR1; NFAT5; TCF7L2; ESR1; ZNF264; DLX5; PEG3; SOX17; MYCL; GATA6; POU2AF1; FLNA; CREB3L2; KDM5D
Down-regulation 46 SHOX2; TAF9; ZNF165; BCL6; TRPS1; PBX3; ID1; CEBPG; ZFP36L2; SOX9; HMGN3; CCNE1; THAP10; KLF7; FOXN3; CUX2; IKBKAP; ZFP36L1; SPDEF; ID4; TRAK1; TCF25; NR2F1; ZNF43; CEBPB; ZNF189; NR2F2; SUPT3H; RERE; RXRA; ETS2; PURA; ZBTB18; TBL1X; TSC22D1; TDP2; FOXD1; NFIB; ZIC1; AHR; INSR; TWIST1; PLAGL1; MECOM; PSIP1; BASP1