Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID23985 Bosutinib GSE70138 NPC.CAS9 Human 24h 0.37uM EID0056
Types Number Response transcription factors
Up-regulation 27 TSC22D3; XBP1; DDIT3; CEBPG; RNF6; RNF10; MLXIP; NFE2L1; ATF4; POU2AF1; YWHAB; ATF5; NFE2L2; RLF; PHIP; CEBPB; TRIM16; SP140L; HOXB2; TRIB3; HOXB7; ZNF721; TFAP2C; LEF1; ZNF160; ESR1; PSIP1
Down-regulation 44 SOX9; GTF2I; CALR; NPAT; MXD4; CBX6; XRCC6; HEY1; TRPS1; SMARCB1; PITX1; ZFHX4; TCF20; CUX2; TCF4; ERBB4; SOX11; DBP; JUNB; SIX2; BAZ1A; ZBTB18; SMARCA1; HLF; MYCN; TOX3; ZIC1; TOX; NFIB; EYA1; NR2F1; NKX3-1; TCF7L2; ZNF22; CTBP2; ID4; BCL3; FOXG1; MAFB; DACH1; PEG3; ID3; ID1; E2F2