Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID23968 Tivozanib GSE70138 NPC.CAS9 Human 24h 0.12uM EID0056
Types Number Response transcription factors
Up-regulation 46 IKZF1; HOXA5; MYB; RELB; ZNF3; HOXA7; PIR; CEBPG; TULP4; BCL3; HOXA4; SSRP1; ZNF45; NFE2L3; ZNF195; IRF4; TP63; KLF13; ZNF721; TCF7; MLXIP; ZBED2; AEBP1; ZBTB18; TCF4; RUNX3; BHLHE41; TRIM29; FOXA2; SNAI2; WT1; PBX3; ARID5B; ID4; FOSB; IRF8; ZNF160; MYRF; TBX3; YBX3; CREB3L2; ID3; LEF1; SATB2; LITAF; TXNIP
Down-regulation 44 KAT6B; SOX11; BAZ2B; SAP30; ZFP36L1; CALR; RBFOX2; JUND; YBX1; LHX2; SALL2; HEY1; ZNF43; PMS1; BAZ1A; ZNF93; PFDN5; PRMT2; BANP; CREB5; EMX2; PHF20; ZIC1; CARHSP1; TSC22D2; DDX17; MEOX2; ZFHX3; ZFPM2; ZNF91; MBD2; FOXC1; SMAD2; SHOX2; ELK3; ZSCAN31; ZFHX4; HEY2; CREM; SMAD1; MECOM; MEIS2; TRIB3; PSIP1