Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID23951	Vorinostat	GSE70138	NPC.CAS9	Human	24h	10uM	EID0056

Response Information :

Types	Number	Response transcription factors
Up-regulation	112	EGR1; FOS; HMG20B; FOXO4; STAT1; TBPL1; DRAP1; NR4A1; JUN; MYCBP; PPARD; FOSB; JUNB; CCNH; CREG1; KLF2; GTF2A2; NFIL3; ATF3; IRF7; SETD3; CRK; CALCOCO1; CBX7; PDLIM1; TSG101; ZNF593; HDAC1; CEBPB; MEF2D; DDIT3; UBE2B; LYL1; NR0B1; DLX4; NR4A2; SND1; CDK7; EGR3; CTR9; CRYM; EVX1; SOX10; TCEB2; KLF10; SIX1; POU4F1; LHX6; FOXC1; MNAT1; HIVEP2; IL16; GATA2; HDAC5; LMCD1; TGFB1; MNX1; DNAJC1; RUVBL2; MLXIP; OSR2; SIRT2; IRF1; PTTG1; SP100; SSX1; AHR; HIPK1; CITED2; NFE2; ETS1; EGR2; SATB2; SERTAD2; NFIC; WWC1; ETV5; TSC22D4; PHF1; MSX1; EGR4; JUND; SNAI2; ECD; HOXD1; NPAS2; SUB1; TP63; PBXIP1; NR4A3; ZBTB20; COPS5; ELF3; SMARCD3; HHEX; RUNX1; MXI1; TOB1; SMARCA2; TRIB3; CREM; ZNF331; KLF6; TFAP2C; JUP; TAF10; CD3D; KLF4; RUNX3; TXNIP; IKBKAP; PSIP1
Down-regulation	263	SOX2; ERBB2; TP53; HMGA2; SMARCA4; PCBD1; ZMIZ1; MTA1; SOX11; PMF1; STAT5B; FOXM1; SMARCC1; ZNF84; MYBL2; SALL1; RFX7; TCERG1; PATZ1; ASXL1; EZH2; DEK; NFKBIA; PHF2; ZFP36L1; PBX3; TSC22D3; ZFY; GABPB1; NUP62; ADNP; ZNF292; ZBED4; BAZ1A; ZKSCAN7; ZFP69B; PLAGL2; HDGF; GLI2; RAN; TADA2A; GTF2I; PITX2; BCLAF1; TGIF2; ZBTB14; SCMH1; VPS72; NRIP1; PARP1; ZNF232; ZNF43; ZNF287; RFXAP; BPTF; TBL1X; ATF1; FOXF1; TLE4; ZNF219; ZBED1; SUV39H2; ZNF85; ZNF107; BRCA2; MEIS1; TAF9B; ZNF227; ZNF614; UBE3A; HOXB5; PBX1; SUV39H1; ZNF141; ZBTB3; APEX1; ZMYND11; WHSC1; ZZZ3; LIN28A; ZHX2; CCNA2; CUX2; ETV1; BRCA1; HOXB9; TGIF1; MLLT10; ZNF236; ZNF529; SMARCB1; YAF2; CHD3; LHX2; NFATC4; TCF4; ZNF532; TAF1D; PPRC1; BRWD1; KLF7; ZBTB1; PRDM10; RBL1; YY1; ZNF189; CTCF; TRAK1; NRF1; HMGB3; HIVEP1; SALL2; ZNF282; ZNF711; BRIP1; YEATS4; HNRNPD; ZFP64; BRD3; ZNF672; RBBP4; CBX5; UBE2L3; SMARCC2; DDX17; SSRP1; PKNOX1; MEIS2; PCGF2; ZNF273; WDHD1; ZNF140; TOX3; BAZ1B; MYCN; E2F3; ZNF22; HOXB6; ZNF253; PCGF3; ZIC3; SMARCE1; CREBZF; SLC2A4RG; FOXK2; MKL2; MED17; RNF111; OLIG2; GLI3; ID4; SMARCA5; ZFP36L2; VEZF1; FOXE1; EHMT2; SIAH2; TRIM22; SP3; BCL11A; ILF2; ZNF202; DEAF1; UBTF; RBPJ; YAP1; ZFX; EMX2; RNF138; ZNF274; RBM39; ZEB1; ARID1A; RARB; NCOR1; PGR; ASCL1; CHD7; NEUROD1; NFYB; RSF1; ZNF146; ZNF45; BACH2; BRD7; HIPK2; ZNF83; CARM1; ZSCAN31; NCOR2; HIRA; ZNF423; FOXO1; NCOA2; MED14; BCOR; E2F8; HAND1; TFEC; REPIN1; CBFB; BCL6; SMAD4; BATF; CARHSP1; CTBP1; E2F5; VGLL4; FOXG1; TRPS1; PBRM1; ARID5B; ZFPM2; ZNF24; ZIC1; ATF7IP; ENO1; AGO2; NCOA6; FUBP1; PHOX2B; HIC2; ABL1; NKX2-1; RREB1; CHD9; SIX2; SMAD3; ZFHX4; C1QBP; TFDP1; IFI16; ERF; PAX5; ZBTB38; CREB5; DAXX; ZEB2; GTF2IRD1; CNOT3; ZNF467; ETV4; SMAD6; FLNA; EYA1; ZNF512B; ARNT2; DACH1; MEOX2; ID3; REL; NR2F1; LOXL2; NFKB1; TCF7L1; INSM1; MECOM; HMGB2; HOXB2; NR2F6; BASP1; GATA6; E2F2