Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID23946 Nvp-bgj398 GSE70138 NPC.CAS9 Human 24h 3.33uM EID0055
Types Number Response transcription factors
Up-regulation 48 TCF7L1; TSC22D3; CALCOCO1; HBP1; PPARG; DLX4; PRDM2; TFAP2A; ZNF83; SMARCD3; ZFPM2; PAX5; DDIT3; ZNF611; POU2AF1; ZNF415; ZNF239; ZFHX4; ARNT2; PBXIP1; ARID5B; FOXF2; TLE2; PDLIM1; HOXC10; FOXG1; ZHX2; SNAI2; ZNF423; RFX5; STAT6; REL; IRF7; IRF9; TRIP6; HOXD1; LITAF; IRF8; ZNF264; BACH2; ZBTB20; TGFB1; MEIS2; ZSCAN18; TRIB3; ID1; BASP1; PSIP1
Down-regulation 27 ETV1; FOSL1; NRIP1; RHOA; MYCBP; HMGA2; BCLAF1; ASCL1; TFDP1; YWHAB; MLXIP; HSBP1; VEZF1; PURA; CBFB; SIAH2; NKX2-1; ENO1; RBBP7; IRX5; ETV5; ELK3; HMGB3; HES1; MYB; NFATC3; E2F2