Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID23741 Wz-4002 GSE70138 NEU Human 24h 0.12uM EID0051
Types Number Response transcription factors
Up-regulation 45 HOXA10; HOXA11; CDK7; GATA3; RBBP8; RUVBL1; OSR2; E2F8; SIM1; ATF5; NPAS2; HOXB2; EMX2; TGFB1; NFE2; HTATIP2; ZHX2; FOSL2; HOXB6; KLF13; HOXC10; TULP3; VGLL1; CCNH; ATN1; PGR; TFAP2A; TCF21; ZBTB16; HHEX; ATF3; LOXL2; TOB1; PSMC3; HLX; FOXO1; ESR1; FOXC1; RUNX1; STAT6; TRIB3; TRPS1; CITED2; MEIS1; LEF1
Down-regulation 48 NFIB; PSIP1; CTBP1; SP110; FOXN3; SUB1; SMARCE1; NR1D2; FOXJ3; ZNF512B; WHSC1; ASCL1; CERS6; RNF4; ZNF721; ZNF302; HLTF; ABL1; HMGN3; ZBTB38; SMARCA2; NAB1; ZNF146; CARHSP1; RBPJ; MYCN; RUNX3; TOX3; RLF; JARID2; ID4; HSBP1; KLF5; NUP62; XBP1; BASP1; BAZ2B; RBBP4; EDF1; TCEB2; MAFB; MED1; KDM5D; DNMT3B; ID1; MAGED1; POU2AF1; SOX9