Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID23707	Ibrutinib	GSE70138	NEU	Human	24h	0.04uM	EID0051

Response Information :

Types	Number	Response transcription factors
Up-regulation	60	HOXA4; HLF; HOXA5; MDM2; RARB; BHLHE41; TP53; HOXD1; BARX2; TAF1C; CCNC; ASH2L; PRMT2; RNF141; MXD1; ELF3; IRF4; GCFC2; IRF5; SUB1; CNOT3; EYA2; MED16; TCF3; MYCL; HOXA1; CTNNB1; CREBL2; IRF1; CALR; LOXL2; MED15; TGFB1; TAL1; CRYM; BATF3; NANOG; SLC2A4RG; FLI1; PNRC1; SOX10; JUNB; CBX7; NKX2-1; MBD2; SATB2; STAT1; TFAP2C; STAT4; NFE2L3; MYBL1; FOXG1; FLNA; SOX9; ESR1; KLF6; MYB; CITED2; TRIB3; POU2AF1
Down-regulation	59	PSMD9; PURA; RUVBL1; ING2; ZBED4; TCF12; RBFOX2; APEX1; MLX; EGR3; FOXA1; CHD9; CREB3L1; ZBTB1; BASP1; RBL2; LIMD1; ZNF281; BCL3; NHLH2; PATZ1; MEIS1; HMBOX1; PAX5; GTF2IRD1; HDAC1; INSM1; BCL6; HDAC4; SMARCE1; JARID2; BRPF1; RBPJ; ZFPM2; MXI1; PBX1; MTDH; TBL1X; NR2F2; HMGB3; BRD4; ZMYND8; MITF; NCOA6; SAP30; ATF4; MNT; ZNF532; CHD7; NAB1; BTG1; AHR; EDF1; DAXX; ZNF131; ZIC1; HHEX; KDM5D; TOX3