Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID23606	Osimertinib	GSE70138	NEU	Human	24h	0.12uM	EID0050

Response Information :

Types	Number	Response transcription factors
Up-regulation	62	STAT3; SMAD2; SMAD4; SATB2; AEBP1; TBX2; UBE2B; TDP2; TOX; MKL2; RREB1; RNF14; LPIN2; ID4; E2F5; NR3C1; SAP30; ZNF217; HMGB3; ELF1; NR2F1; CARHSP1; CDYL; EGR3; PIAS2; SMAD6; ELF5; CSDE1; IRX5; ZNF24; UBE2I; PHF20; ID2; RBBP4; MAFG; PEX2; HMGB2; CEBPB; ARID5B; KLF10; VDR; RUNX1; DLX2; FOXF1; TXNIP; ID3; TCEB2; ETS2; ZEB1; CITED2; BRD3; ID1; RBBP8; TFAP2C; ZNF589; EDF1; KLF5; SATB1; TLE4; TOX3; PSIP1; BASP1
Down-regulation	61	HMG20B; MED15; TFEC; SIX2; NFIC; PITX1; SSRP1; ZNF239; HHEX; TFEB; GLI2; MAFF; MYBL2; FOSL2; RBPMS; PCBD1; ZNF266; EYA2; CREB3L2; ZNF83; APEX1; NR1H3; CREB5; MITF; IFI16; ZNF467; BNC2; CHD9; MYCL; NKX2-2; ZNF573; ZNF415; HIC2; ECD; YEATS4; ATF3; ZNF512B; ZBTB38; ZNF331; ESR1; NKX3-1; SLC2A4RG; MYRF; ELF3; KLF6; ST18; SOX17; YBX3; TGFB1; TRIP6; FOSB; SHOX2; PEG3; ZBED2; ZNF131; ZNF264; MNDA; HOXC10; ZNF91; BHLHE41; GATA3