Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID23603	Osimertinib	GSE70138	NEU	Human	24h	3.33uM	EID0050

Response Information :

Types	Number	Response transcription factors
Up-regulation	79	KDM5A; E2F2; BATF3; TCFL5; PCGF3; RNF4; FOXJ1; ZNF652; MYCBP; NR1D2; INSM1; TBX2; TXNIP; FOXO4; TMF1; NEUROD1; ASCL1; SIX2; ZBTB43; RBL2; SFPQ; NFX1; SP100; PAX6; ZBED1; FOXA1; CREB3L1; CERS6; PBRM1; NR1I2; ZNF148; IRX5; EYA1; TCF4; MEOX2; ZNF721; RNF6; ZNF516; PDLIM1; RNF138; CHD7; MEIS1; POU3F2; CREB3; SMAD5; OLIG2; NFAT5; KAT2B; MECOM; CITED1; ZNF43; BRD2; MYT1L; ZNF160; PURA; ISL1; SMARCA2; BAZ2B; SMARCA1; TBL1X; RORA; HOXB6; PHF20; SATB1; BBX; KDM5D; NR2F2; TOX3; ZIC1; ZBTB20; EMX2; MSX1; FOXG1; MAGED1; KLF5; ZMYM2; BASP1; SPEN; PSIP1
Down-regulation	58	MTA1; PIAS4; LOXL2; LIN28A; ZNF580; LMCD1; PPP1R13L; ID1; HDAC9; POU2AF1; C1QBP; JUP; CEBPB; CALR; NANOG; XRCC6; TAL1; ZNF593; RBPMS; LITAF; TCF7L2; SAFB2; TRPS1; ZBED2; TRIM16; JUND; TCF3; ITGB3BP; ZFP36L2; NFE2L3; FOXE1; ZNF217; ZNF239; ZNF557; ZHX2; TBX3; BHLHE41; MAF; ST18; TRIB3; SUB1; TFAP2C; GCFC2; ID3; ZBTB16; SOX9; SLC2A4RG; ZNF281; HOXC10; TRIM29; YBX3; MAFB; IRF6; HOXC6; CITED2; GATA6; NR1H2; GATA3