Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID23595	Motesanib	GSE70138	NEU	Human	24h	0.04uM	EID0050

Response Information :

Types	Number	Response transcription factors
Up-regulation	70	HOXD10; RNF4; FHL5; AATF; ARRB1; MKL2; HOXB7; SMARCA2; TOX; ELF4; PCGF3; HNRNPD; BATF; CDYL; ERG; IRX5; EGR4; SMAD7; DBP; HOXB6; MEOX2; EGR3; RUNX3; NEUROD1; NONO; CHD3; TDP2; TRIM32; CCNE1; EYA2; POU3F2; ENO1; SMARCD3; ID2; FOXA1; PITX2; KDM2A; KDM5B; HSBP1; CITED1; HLTF; CREB3; ETV5; NR2F1; ZNF248; NKX2-1; NCOA4; STAT4; ASCL1; NCOA1; TLE2; MYT1L; GTF3A; ZEB2; MSX1; FOXC1; HMGB3; MAGED1; PURA; SMARCA1; MAF; FOXG1; MYCN; PCGF2; CITED2; MEIS1; ZMYM2; BMI1; ZBTB18; PSIP1
Down-regulation	85	MTA1; MTF2; HDAC4; PITX1; TRIB3; ID1; HOXC11; CBX6; BCL11A; LMCD1; TCF3; CEBPB; NFKB2; POU2AF1; ZNF232; SREBF2; ZNF593; EN1; BACH1; LEF1; ZNF12; LIMD1; LITAF; IRF3; CTNNB1; ZFP36L2; CSDE1; NFE2L3; TFCP2; KLF2; TRPS1; TBX3; IRF9; CERS6; RBBP8; PTRF; CALR; ZNF551; ZNF136; PBX3; TOB1; CREB3L2; FOSB; SNAI2; ZFP36L1; ZBTB20; TRIM22; EHF; TRIM29; ZNF226; PAWR; SALL1; JUNB; LOXL2; SUB1; TFAP2A; NFE2L2; ZNF264; CBX7; GATA6; IRF6; CRYM; KLF6; ZNF195; SOX9; IRF8; RBPMS; ZNF131; SLC2A4RG; CDK2; TWIST1; HOXC10; TP63; OSR2; BTG1; ZBED2; HOXA10; HOXC6; GATA2; NR1H2; MYBL1; YBX3; ZNF91; SMAD3; GATA3