Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID23594	Motesanib	GSE70138	NEU	Human	24h	0.12uM	EID0050

Response Information :

Types	Number	Response transcription factors
Up-regulation	80	STAT3; E2F2; HMG20B; KMT2A; IRX5; DEAF1; NCOA4; CHD9; ZNF629; SIAH2; ENO1; SCAND1; CHD1; TCF25; MYCN; RHOA; HMGN3; PQBP1; ARID4B; HOXC6; SMARCA1; HNRNPD; POLR2A; DDX5; SFPQ; RNF14; ZKSCAN7; EDF1; BCLAF1; ZNF430; ZBED1; LHX2; SMARCA5; NKX2-2; NEDD8; MYT1L; CREB5; BATF; AES; BAZ1A; TFEC; RUNX3; MED13; ZNF516; TCF4; RBM14; TCF7; MTF2; ZBTB18; ETS2; ZNF468; OLIG2; ZNF721; CBX3; PATZ1; INSR; MEIS1; HMGB3; SOX2; MAGED1; SETD2; SMARCC1; FOXO3; MSX1; BAZ2B; ZEB2; FUBP1; ZNF131; TCEB2; ZNF160; ZBTB38; CARHSP1; HOXB2; ZNF91; ZMYM2; NFIB; KLF2; BASP1; PSIP1; PEG3
Down-regulation	105	NFKBIB; HBP1; DDIT3; GMNN; TDP2; CALR; HDAC9; AEBP1; TRAF6; CDC5L; JUNB; TAF5; GATA6; SP100; ARNT2; PPP1R13L; ZNF33B; CEBPG; TFAP2A; TCF21; FOXF2; TTF2; ATF3; EGR1; SUPT5H; MYBL2; SOX13; WWTR1; MBD2; SNAI2; ZFPM2; TP63; LOXL2; ZFP36L1; DNAJC2; PAWR; YEATS4; HIRA; COPS5; SMAD6; NFE2L3; FOXM1; EHF; EN1; KLF9; TRIB3; MAFF; ZNF331; MEIS2; SIX6; BACH2; ANKRD1; HMGA1; BNC2; TGFB1; ISL1; GCFC2; TULP3; ZNF423; TAL1; ZEB1; PLAG1; HEY1; ACTL6A; FOXF1; ZNF557; TOB1; MITF; CREBL2; NCOA2; HOXD1; STAT6; SSX1; ELF5; CNOT3; TRIP6; PDLIM1; NFE2L2; MECOM; JUP; ID3; MEOX2; NR2F1; FOXD1; MXI1; OSR2; KLF5; IFI16; TRIM29; NR4A2; RBPMS; PIR; MAF; KLF4; MYRF; IRF6; ID1; SATB1; LEF1; ZBED2; NR1H2; SOX9; SMAD3; IKZF1; BHLHE41