Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID23535 Pf-04217903 GSE70138 NEU Human 24h 0.37uM EID0050
Types Number Response transcription factors
Up-regulation 63 E2F2; EPAS1; TAF1D; GTF2I; GABPA; RBL2; NEUROD1; PATZ1; INSM1; RFX7; TXNIP; YAP1; RERE; MLLT10; BTAF1; ING2; BACH2; HMBOX1; BIRC2; POU3F2; ZNF24; RNF138; RBPJ; ZNF248; BTG1; HIVEP2; YBX1; PURA; ZNF711; HLF; HIPK3; PBX3; FUBP1; CUX1; ZIC1; TAF9B; RYBP; TSC22D1; EGR3; MED1; SMARCA5; NR1D2; CHD7; NR4A1; TOX3; NKX2-2; SATB2; MAF; PAWR; SMARCE1; ZBTB1; ZNF189; KLF9; FOSL2; ZBTB18; ZBTB20; FOXG1; RBBP4; SATB1; LEF1; PCGF2; ZMYM2; BASP1
Down-regulation 55 NPAS2; KAT6B; HSF1; TGFB1I1; ZNF423; IRF9; E2F8; TDP2; HOXB7; LMCD1; CD3D; HMGA1; PSIP1; TCF7; ELF3; TCEA1; ZNF232; ZSCAN18; TOX; FOXN3; JUN; MEOX1; POU2AF1; BCL3; TFAP2C; LOXL2; TFCP2; TERF1; HOXB13; ZNF350; CRYM; NFE2L2; MEIS2; HIRA; HOXB6; ZEB1; SMAD7; TGFB1; ERBB4; HOXB2; TWIST1; ELK3; TRIB3; SLC2A4RG; MYBL1; TFAP2A; NR2F2; NR2F6; TRIM29; ZFPM2; ESR1; ZNF264; KLF2; NR1H2; ZNF91