Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID23519 Bix-02189 GSE70138 NEU Human 24h 0.04uM EID0050
Types Number Response transcription factors
Up-regulation 62 EGR1; LOXL2; ZSCAN31; JUNB; ZNF134; CNOT3; ZNF227; ZNF586; CREBL2; POU4F1; ZNF304; NR3C1; ELF3; HEY2; DDIT3; IRF1; MECOM; HOXB7; SOX17; JUP; ZNF423; TOX; EYA2; CEBPZ; TFAP2C; PITX1; HMGA1; CREM; ZNF551; TGFB1; ZNF211; LIN28A; HDAC9; ZNF165; PDLIM1; NEUROD1; CEBPG; EGR2; WWTR1; ATF3; SPDEF; TLE2; ZNF329; HHEX; PLAGL1; KLF11; SALL1; TWIST1; LITAF; FOXD1; FOXF2; EHF; ID3; KLF5; KLF2; BHLHE41; ID1; TSC22D1; CEBPD; ZNF91; MYBL1; TOX3
Down-regulation 66 TBL1XR1; GABPB1; SP2; ARID1A; CHD9; ZBTB16; HMGXB4; SPEN; SALL2; ZNF22; THAP4; MLX; PMF1; UBE3A; COPS5; RREB1; SMAD4; HMG20A; HMBOX1; CREB3L2; ZNF131; DMTF1; ZBTB11; MTDH; TRRAP; HDAC1; EYA1; CREB3L1; DACH1; HOXA11; PRKDC; NR2C1; GLI3; RAD21; TAF1D; CUX1; SREBF1; SOX2; TCF12; ETS1; EGR3; MED23; MAFG; LMCD1; YWHAB; INSR; ZMYM2; TCF4; PBX3; RBBP8; IRX5; CUX2; CHD7; TLE4; MAGED1; CBX3; IRF4; IRF7; RYBP; SMARCD3; JARID2; IRF8; HMGB3; NR2F2; HOXC6; NFATC3