Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID23513 Cgp-60474 GSE70138 NEU Human 24h 0.04uM EID0050
Types Number Response transcription factors
Up-regulation 346 EGR1; VDR; HOXD11; TFDP3; ZNF33B; SSX3; HOXC4; NFATC4; PRDM14; SRY; GBX1; PAX2; ASH1L; TAF4B; HOXA10; LMX1B; HOXC8; ARID3A; PPARD; NRL; HOXA7; KLF9; EMX1; VGLL1; LHX3; ZSCAN2; HOXD1; OVOL1; HDAC9; JUNB; CHD2; ESR1; THRB; HOXD9; RBPJL; SSX1; HOXD10; TBX21; PPP1R13L; PML; PAX7; E2F4; AIP; ESRRA; CBFA2T3; HOXA1; HOXA11; EMX2; NR1I3; SRF; SNAI2; ZNF324B; HNF1B; IRF5; CBX8; ZKSCAN3; NEUROG3; NR0B2; POLR3C; HOXB7; ATOH1; GATA1; BNC1; CAMTA2; TOB1; HOXB9; ZNF215; PRDM1; TRIP4; RARG; RFX2; VENTX; HOXC5; HEYL; PITX3; NFKB2; HDAC11; DOT1L; SSX7; HIPK2; TBX2; NAB2; HOXC6; CCNH; RFX1; CBX2; PAX8; PROP1; MYBL2; RBPMS; ZNF695; HIVEP3; CDX1; JUP; ALX4; TP73; NKX2-8; CDIP1; SNAI1; PSMD9; GON4L; TULP1; ZNF467; AEBP1; STAT4; TONSL; YBX2; MLLT1; PSMC3; CCNE1; CNOT1; ZNF507; EYA3; HSF4; TFDP2; ZBTB16; WT1; LHX6; HOXD3; HLX; CDX4; ETS1; NR0B1; ETV7; SMARCD2; MED15; FOXB1; KDM4C; POU2F2; FOXI1; CBX6; ZIM2; IRF1; PRDM8; TFAP4; MAML3; TRIB3; NFE2L3; SOX21; POU4F1; ONECUT1; LOXL2; HOXB6; MLXIPL; CALR; SIX5; PRDM2; TAF5L; TFAP2C; HOXA2; TLX3; HIF3A; TAF1C; TEF; PAX9; TLX2; GFI1; CDX2; KLF15; TTF2; ZNF778; ZNF75D; KLF11; ZNF701; ZNF343; TULP2; ZNF154; BHLHE40; IRF6; SP4; SP140L; SHOX; TUB; DLX4; LYL1; NR5A2; POU6F1; MDM2; ZNF394; SP1; MYBBP1A; E2F1; ZNF335; ZNF771; ZNF141; HESX1; CIITA; NR1I2; TGFB1; ARNTL2; NFE2L2; TRIP11; IKZF2; NFX1; LZTR1; C1QBP; ZNF257; LMCD1; POU6F2; PRDM5; BARX2; TBX5; ZBTB48; ZKSCAN4; SCRT1; GCFC2; SRCAP; CHAF1B; NR1H4; ZXDC; PCBD1; TAF1; HOXB1; MED31; KLF3; FOS; ATF3; CBX7; RUVBL1; JAK2; SOX18; IRF9; IFI16; HOXA6; ATN1; ZNF205; PRRX1; ZNF224; IRF3; CBX4; TRIP6; MNX1; MBD2; SKIL; PGR; KLF4; CD3D; PFDN5; ECD; BAZ2A; HDAC6; MED25; STAT2; IFNB1; PRMT2; ELF4; NSD1; SND1; MYRF; CEBPE; SLC2A4RG; HOXB2; REL; TCF21; HOXC10; CCNT1; ZBED2; HOXC11; EHF; HTATIP2; CREB3L2; AES; TFAP2A; ZBTB44; PA2G4; NHLH1; MEF2A; SP100; TWIST1; THAP11; EN1; NFATC1; MAFF; SPDEF; ZBTB20; FOSB; PTRF; SOHLH2; TGFB1I1; RUNX1; ZNF552; ZNF768; GRHL2; FOXA2; SUPT3H; FLI1; RBL2; MNDA; BARX1; EGR3; ZNF652; FOXD1; NR4A2; SUPT6H; EGR4; SMAD1; ELF3; ANKRD1; ZNF557; FOXL2; NEUROD1; CREM; THAP10; ELF5; TEAD4; PPARG; ST18; ARID5B; TERF2; IL16; CDK2; KLF13; E2F8; CRYM; NR2F6; MED21; XBP1; EPAS1; ZNF423; WWC1; IRF4; GATA6; KLF6; BNC2; CNOT3; TLE2; ZNF264; PLAGL1; MYBL1; SOX17; FHL2; TULP3; NANOG; ZBTB38; STAT6; TRIM22; ZFPM2; MEF2C; CITED2; CEBPB; HES1; PDLIM1; CEBPD; KLF2; OSR2; CREB1
Down-regulation 253 SOX4; USP22; HDAC2; SUZ12; SMAD2; ABL1; PBX3; VEZF1; CHD8; HSF2; NONO; SOX11; PUF60; SSBP2; JARID2; RBBP4; KAT7; APEX1; YBX1; EYA1; BASP1; ZNF292; BCLAF1; ZBTB11; SMARCA4; E2F5; BCOR; ZNF3; KAT6A; ZNF468; RNF10; TAF1D; DNMT3B; TBPL1; ARID4B; E2F3; PCGF2; HEY1; TBL1XR1; PRKDC; NUP62; ING2; GTF2A2; CTBP1; UBE2I; CRY1; RBPJ; EZH2; SCAND1; TCF12; MED23; ZEB1; ZNF14; NRBF2; MYT1; BIRC2; BRD3; TCERG1; PMF1; DDX5; MED17; TSC22D1; RERE; KDM5B; HIF1A; VGLL4; CHD7; TCF4; INSM1; SALL2; RHOA; RLF; HEY2; ZFHX4; RCOR3; TLE1; NCOR2; TOX3; ISL1; HDAC4; CBX5; ZBED4; FLNA; HDAC1; CBFB; FUBP1; MYT1L; ZNF24; NRIP1; PHF2; CBX3; HSBP1; KMT5A; DEK; FOXJ3; ZSCAN18; NFIL3; SUMO1; ADNP2; SMARCA5; SIX2; HNRNPD; ZBTB18; ZNF146; RNF4; NCOA4; ZNF432; ZNF529; NEDD8; RAD21; BAZ2B; ZNF532; TBP; RNF138; PATZ1; ELF2; ZNF516; ATF2; NKX3-1; PHIP; ATF4; DDX17; SSRP1; WHSC1; TRAK1; OLIG2; CREB5; FOSL2; HMGB2; ZNF443; ZNF302; ADNP; KDM5D; YWHAB; CTBP2; ZBTB1; ZMYM2; ZNF43; FOXO4; ZNF813; TAF12; MAGED1; RAN; RFX7; ID4; SATB1; REPIN1; MTF2; MEIS1; ZNF587; CHD1; DEAF1; NFE2L1; TBL1X; BRPF1; NKX2-2; ZKSCAN7; SMAD4; HMGB3; BRD8; ZNF84; MYCBP; SMARCC1; BMI1; SIX1; SFPQ; HIPK1; FOXO3; ZMYND8; SOX2; FOXK2; HMG20A; ID1; NFYC; WWTR1; ZNF83; MGA; KMT2A; PEX2; MYCN; ZNF267; PBRM1; PQBP1; CAMTA1; ARID1A; ZNF512B; ZNF268; TAF7; ZMIZ1; TBX3; MAZ; TAF10; JUND; LZTS1; RCOR1; CENPB; SMARCA1; RBM14; IKBKAP; ENO1; ARID4A; HMGB1; HMGN3; CENPF; ZNF419; ZNF562; HIC2; PSPC1; BCL6; ZNF266; SMAD5; TLE4; MED24; FOXF1; ZNF606; ZNF711; IRX5; PBX1; EDF1; SMARCD3; BTG1; BACH2; SMARCA2; SAP30; RFX5; RBM39; HMBOX1; CITED1; MEIS2; SETD2; CSDE1; ZNF117; ZNF189; ZNF721; RRN3; CTR9; FOXG1; MED1; TULP4; MYB; ID3; DACH1; NCOA1; ZNF160; SPEN; ASCL1; PIR; ZNF131; MSX1; ZNF281; MXI1; NFIB; PEG3