Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID23505	Tivozanib	GSE70138	NEU	Human	24h	0.12uM	EID0050

Response Information :

Types	Number	Response transcription factors
Up-regulation	138	EPAS1; ELK4; YAP1; PGR; PTRF; NFATC4; MECOM; SP1; CALR; TAF6L; EHF; TRIM25; SOX17; NFYA; MYNN; ZNF224; FHL5; HIF3A; SKIL; RFX1; PRMT2; FOXM1; BARX1; REL; NR0B2; ATF5; GATA1; AFF4; HDAC9; ZNF816; HNF4G; VDR; PPARA; PRRX1; JUP; ESR1; ZHX2; THRB; NR5A2; CREM; MEOX1; AEBP1; EMX2; TGIF2; SMARCD2; NFE2L3; ZBTB20; HOXB5; PCBD1; MYBL2; TRPS1; PPP1R13L; JAK2; SP140L; GCFC2; HHEX; SP100; ZNF770; CBX7; CEBPE; NR4A3; TRIB3; GATA6; HIPK3; NFKB2; LOXL2; ZNF205; TAL1; CCNH; BCL11A; TAF1C; FOXA2; PAWR; KLF9; IRF1; VGLL1; MED21; SLC2A4RG; SRCAP; JUN; POLR3C; MAFF; SIX6; SOX18; CEBPG; ATN1; ZNF623; HOXB2; NFE2L2; GTF2I; RFXANK; STAT4; WWTR1; ERG; MBD2; ELF5; CNOT3; FOXF2; ETS1; KLF4; NFATC3; IRF6; NR4A2; MNDA; TFEC; TCF21; CREG1; MYBL1; ZNF394; ZBTB16; TFAP2A; SNAI2; ZFPM2; NR2F6; ETV5; CREBL2; HOXD1; RORA; NR0B1; ZNF423; WT1; FOSB; RBPMS; HLF; TOB1; CDK2; HOXC10; SHOX2; AHR; PIR; TRIM16; ZBED2; MYCL; TRIM22; ZNF589; ID1; KLF2; KLF5
Down-regulation	146	HMGN3; TSC22D3; USP22; KDM5B; SOX4; HNRNPD; CTBP1; KAT6A; BASP1; APEX1; NONO; SIX1; GABPB1; NCOR2; CHD1; ASCL1; ING2; FOXJ3; WHSC1; AFF1; REPIN1; ABL1; YBX1; ZNF516; TSC22D1; PUF60; DNMT3B; BRD8; PCGF2; USP21; BTF3; DRAP1; KAT8; HDAC1; ZNF146; NEDD8; EZH2; TRIM24; HSF2; TBL1X; HSBP1; MAGED1; ZNF711; SOX11; INSR; BRD3; TSG101; HIC2; NUP62; NCOA6; RNF10; TRIM28; SMAD2; HIF1A; ELF2; EYA1; PARP1; RNF4; MYT1L; JARID2; RBPJ; PCGF3; TCERG1; ARID4B; YWHAB; ZNF117; RBBP4; PQBP1; KMT2A; MED1; SMARCA4; HDAC2; BCLAF1; MED23; ZNF22; SAP30; PKNOX1; ZBTB18; CBX3; OLIG2; HMGB3; HDGF; MNT; ZNF468; IRX5; ZNF302; UBE3A; HMGB1; RBM39; ID3; POU2AF1; TBX2; ERBB2; MAZ; TLE4; DMTF1; DPF2; NKX2-2; NCOA4; ARID4A; TLE1; URI1; SATB1; HEY1; GTF2IRD1; ATF4; PITX1; PBRM1; ING3; BAZ2B; SALL1; ZNF83; ETS2; ZNF721; ADNP; ZNF532; SUB1; RLF; KLF10; SCAND1; BMI1; ZNF160; SATB2; PEG3; SMARCA5; TULP4; ZEB2; HLTF; SMAD1; PURA; TBX3; SMARCD3; TXNIP; NKX3-1; TCF4; MSX1; ZNF91; ZNF189; HOXC6; FOXG1; KDM5D; NR2F2; ZMIZ1; LEF1; MAFB; ZMYM2