Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID23502 Tivozanib GSE70138 NEU Human 24h 3.33uM EID0050
Types Number Response transcription factors
Up-regulation 47 HDAC9; FOXM1; VDR; ZNF331; MEF2A; JUP; BNC1; ELF4; CENPF; PAX6; PPP1R13L; RUNX1; TWIST1; IRF1; ATN1; TGFB1I1; LOXL2; SOX13; CALR; ZHX2; PITX2; SERTAD2; AEBP1; HMGB2; EN1; BNC2; TULP3; CNOT3; FOSL2; ZNF217; TFAP2C; MKL2; GATA6; TCF21; IRF6; PAWR; RBPMS; TRIM29; CDK2; TRIB3; NR4A2; FOXD1; NR2F6; FOXF2; TFAP2A; SNAI2; TRPS1
Down-regulation 63 HMG20B; HMGN3; ASCL1; ZNF516; FOXO1; SALL1; HEY2; TCF15; PSIP1; PIAS2; FOXJ3; YWHAB; JARID2; CNOT2; TBL1X; TGIF1; TBL1XR1; ATF5; PEG3; TRIM32; DNMT3B; RBBP4; IRF4; TSC22D1; KAT7; ING3; POU2AF1; TERF1; MITF; ZBTB38; RBPJ; HSBP1; MSX1; HTATIP2; ERBB2; FOXO3; IRX5; ZBTB1; EGR2; TXNIP; PURA; SMARCA2; TOX3; ZSCAN18; MAF; MYCN; ID1; BTG1; TCEB2; SATB1; SMARCD3; DAXX; PIR; ZEB2; ID4; ZMYND8; FOXG1; NFIB; TBX3; NR2F1; MAGED1; ZBTB18; ZNF586