Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID23474	Idelalisib	GSE70138	NEU	Human	24h	0.37uM	EID0049

Response Information :

Types	Number	Response transcription factors
Up-regulation	96	ING1; ZBTB14; RNF10; CREG1; MXI1; GTF2IRD1; LEF1; RBPJ; YWHAB; MAFG; ING2; TBL1XR1; ZNF711; CREB3L1; ERBB2; TSC22D1; CIZ1; NFATC3; KAT5; BRPF1; CRY1; SMARCE1; NLK; KLF5; ZBTB18; BRD3; CHD7; SOX2; FOXO4; MYT1L; ZBTB1; RCOR3; RAN; ZNF43; PIAS2; SMARCA5; IRX5; TCF4; RFX7; NFIB; ZNF443; BRD8; SATB2; MYCN; EGR3; INSM1; ZNF131; TAF1D; BATF; ZNF84; NCOA6; ZMYM2; ADNP; ZNF281; EGR2; NKX2-2; RBM14; EDF1; SAP30; TOX3; VGLL4; HIVEP2; RFX5; MED24; KDM5B; PEG3; ZNF652; HSF2; ARID4B; SETD2; ZEB2; ARID4A; SMARCD3; BASP1; ZMIZ1; MAFB; TOB1; HDAC2; TLE1; PATZ1; MTF2; NUP62; SATB1; PHF20; RBBP4; ZMYND8; ZNF91; NRIP1; BMI1; MED1; TWIST1; ZIC1; KDM5D; JARID2; MAGED1; SMARCA4
Down-regulation	120	WWTR1; AR; GATA4; ARID5A; TCEA1; TFAP2C; TCF7L2; JUND; FLI1; BARX2; ZNF589; SUB1; RUNX1; LYL1; OSR2; ZXDC; ATN1; NKX2-1; ZFP36L2; ZSCAN31; TDP2; TTF2; C1QBP; CERS4; HOXB2; NR0B1; SP140L; TCF21; HMGA1; MYNN; TBX5; ACTL6A; RBPMS; FOXF2; PRRX1; TRIP11; SRCAP; MDM2; KLF10; EHF; PBXIP1; SOX13; HHEX; PIR; ZNF623; TP63; FLNA; ESR1; NR2F6; EN1; HIPK1; LMCD1; IRF4; MEIS2; TRIM22; BNC1; HIF1A; ZBED2; CEBPB; SPDEF; ELF5; E2F8; NR5A2; TGFB1I1; CBX7; PCBD1; STAT4; AEBP1; PNRC1; TCF7L1; TRIP6; WT1; PSMC3; ZNF215; ERBB4; ETS1; ZHX2; NFKB2; GATA6; JUNB; NR1H2; SHOX2; HDAC9; NFATC4; ZNF394; SNAI2; SOX17; MYBL1; KLF2; IRF6; DLX5; LOXL2; CCNH; PSIP1; ZNF557; WWP1; SLC2A4RG; NR4A2; CDK2; ZEB1; CRYM; KLF9; KLF11; HOXD1; TGFB1; RBBP8; VDR; TFAP2A; HOXB7; CEBPD; ZBTB16; HLX; IFI16; GATA3; EMX2; TRIB3; HES1; ARID5B; HOXB6; MEF2C