Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID23473 Idelalisib GSE70138 NEU Human 24h 1.11uM EID0049
Types Number Response transcription factors
Up-regulation 65 ADRB2; CREG1; SAP30; TSC22D1; MEF2C; TBX3; ILF2; MSX1; DLX2; AHR; YBX1; MEOX2; CEBPG; FOXG1; SALL1; HMGB2; GTF3A; CBX3; IRX5; MAF; BIRC2; CRY1; STAT4; SOHLH2; ZEB2; ID3; NR1H3; MEOX1; CTBP2; SSX1; SMARCE1; KLF5; HMGB1; YBX3; NKX2-2; BTG1; KLF10; HEY2; RBPJ; PDLIM1; EGR3; ZNF131; NKX3-1; NR3C2; ID2; SOX9; EYA1; HIPK3; ETS2; EGR2; DACH1; PBX1; PHF20; TXNIP; ID1; BMI1; KLF2; HMGN3; MEIS1; SNAI2; BASP1; NRIP1; MYBL1; TOX3; PSIP1
Down-regulation 54 IL16; MZF1; ETV6; ZNF107; BNC2; ZNF224; ZNF83; MED14; ZBTB20; CIZ1; ERG; ELK4; MDM2; AGO2; IRF4; FOXO1; BCL3; BATF3; CDK9; ZNF552; IRX4; CHD9; DMTF1; CBX7; RUNX1; INSR; CAMTA2; PPP1R13L; ATF5; FOXC1; BCL11A; WWTR1; ATN1; KMT2A; TCF21; IRF8; TAL1; NFATC4; TRIM29; TULP4; VDR; TRPS1; KLF13; NR4A2; PAX5; ETS1; MYRF; HLX; WWC1; ASCL1; AEBP1; ESR1; NFATC3; GATA3