Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID23452	Osimertinib	GSE70138	NEU	Human	24h	0.04uM	EID0049

Response Information :

Types	Number	Response transcription factors
Up-regulation	111	SUV39H1; ZNF586; ZNF134; NEUROD1; COPS2; ZNF324; FOXH1; TFE3; ZNF264; LIN28A; HINFP; ZNF44; ZNF606; AR; DDIT3; OSR2; ZNF415; TGIF1; ZNF552; FOXL2; ELF4; MEOX2; ZNF85; ZNF211; ZNF544; ZNF654; FOXG1; ZNF419; PQBP1; ATF3; ZNF304; ZNF580; LITAF; ZNF136; HOXB2; BRD4; NANOG; POU5F1B; SOX13; HAND1; TCEA1; RBPMS; ZNF551; RNF6; PGR; IRF1; SNAI1; PRDM1; KLF1; EYA2; GTF3A; SIX3; GATA3; MSC; BNC2; EGR2; IRF3; MECOM; SOX17; HOXC4; ZNF331; ESR1; TDP2; ZNF93; ZNF611; MITF; HOXB5; ZSCAN18; ZNF430; LOXL2; PFDN5; ZNF665; TRIM28; ZNF217; TULP3; ELF3; KLF6; PLAGL1; MSX1; ZNF587; NR1H3; JUP; TFEC; SPIB; ATN1; INSM1; FOXM1; HMGB3; SMAD7; YBX3; PA2G4; EMX2; KLF13; HOXB6; ZFP36L2; TEAD4; NR4A1; STAT6; FOXF2; ZNF281; HOXD1; ZNF91; TSC22D1; CALR; HLX; TRIB3; IRF6; SNAI2; GATA6; TCF21; ZBTB18
Down-regulation	100	NCOA3; TCF7L2; L3MBTL1; DNAJC1; NFIB; PKNOX2; CDK8; TRIM29; JUND; PMS1; FOXC1; PBXIP1; CERS6; ZNF184; GATAD2A; LEF1; PPARGC1A; FOXN3; ELK3; MAX; MAFB; NFAT5; SREBF2; CTBP1; TERF2; E2F3; EHMT2; HDAC4; PRKDC; MYB; KDM5D; DMTF1; SMAD4; CEBPB; RFX7; NCOR2; DEAF1; POU2AF1; DNAJC2; ZFHX3; NR0B1; INSR; NR2F1; SMAD2; NR2F2; CHD1; NFYC; ZMYND11; ERG; CRY1; BAZ1A; ZBTB38; SCAND1; CHD9; KLF11; NAB1; RUNX1; HIVEP2; NPAS2; CREB3L2; ISL1; SFPQ; WWC1; RFX5; SMARCA2; POU4F1; SOX9; RUNX3; ZNF24; PSIP1; DNMT3B; MAGED1; ID4; ZEB2; ZMYND8; ZNF292; PATZ1; ASCL1; TLE1; EYA1; HHEX; BMI1; TXNIP; ZBTB16; PHF20; ID1; FOXJ3; HMGN3; CITED1; TOX3; SMARCD3; BCL11B; MYCN; MED1; JARID2; CHD7; KLF2; AEBP1; BASP1; NFATC3