Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID23451	Osimertinib	GSE70138	NEU	Human	24h	0.12uM	EID0049

Response Information :

Types	Number	Response transcription factors
Up-regulation	86	PLAGL1; MXD1; SOX9; KLF5; TRIM29; JAK2; NKX3-1; MED17; BTG1; TOPORS; FLNA; OVOL1; RARG; JUP; ZNF175; TAF12; PRRX2; CIZ1; SSBP3; ZNF264; THRA; WWTR1; IRF1; CREG1; TBL1XR1; HOXC10; TP63; RRN3; KLF10; CDX1; CREB3L2; MYB; ZNF551; PPP1R13L; TBX3; BCL11A; NR1H3; SMAD4; ZBTB43; EGR4; ID4; TFEC; ZNF611; IRF5; ZNF160; RAD21; BACH1; MXI1; BHLHE41; SP140L; SUB1; PEG3; SPIB; ID3; DLX2; NFATC3; PTRF; INSM1; NR4A2; ERG; UBE2I; WWP1; SNAI2; PAWR; ZBED2; CRYM; RUNX1; HOXD1; TRIM22; GATA6; IRF8; NR4A1; NR1H2; EYA1; CALR; STAT6; TCF21; TSC22D1; TLE4; IRF6; IFI16; ARID5B; TFAP2A; TRIB3; TRIP6; PSIP1
Down-regulation	99	ZMIZ1; PSMD9; PLAG1; CBX6; JUND; SMAD1; NCOR2; GTF3A; ARRB1; CTBP1; CENPF; CBFB; SREBF1; GFI1; ZNF23; ATF6; COPS5; TAF9; XRCC6; ZNF43; NEDD8; COPS2; HNRNPD; ZNF410; TCF25; MDM2; TSG101; YWHAB; DEAF1; CBFA2T2; GTF2IRD1; POU3F2; MGA; BRD4; FOXA2; RBPJ; FOXO1; CREB5; TERF2; PBX1; NFIC; ZFP36L2; MSX1; RERE; LITAF; EP400; KAT6A; NCOA6; ZNF281; HMBOX1; MITF; SHOX2; PURA; ETV5; TRAK1; BANP; GLI3; ZNF91; PHF20; SMAD7; HMGA1; NR1D2; ZNF423; BCL6; TLE2; BNC2; CARM1; BTF3; ZNF516; MAGED1; POU2AF1; WHSC1; ELK3; SALL1; MYT1L; MNT; LEF1; CHD3; EMX2; RBM39; SOX2; ZMYND8; BACH2; SATB1; HSBP1; RORA; HEY1; ZIC1; TOX; PATZ1; LOXL2; DDX17; CITED1; PCGF2; TCF4; HOXB6; ID1; TOX3; BASP1