Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID23439	Motesanib	GSE70138	NEU	Human	24h	0.12uM	EID0049

Response Information :

Types	Number	Response transcription factors
Up-regulation	103	PPARG; SSX1; EBF2; NFX1; MLX; STAT4; PRDM5; LPIN2; FHL2; STAT5A; FOXD1; SOHLH2; TBX21; NR1H3; SATB2; EYA2; FOXA1; SMARCA1; YBX2; TRIM24; PITX2; SCMH1; SIX2; HEY1; RNF10; RUNX3; LHX2; SND1; MYT1; NELFB; PLAGL1; REPIN1; TRIM16; ALX1; TGIF1; PLAG1; FOXE1; SREBF1; ENO1; DNAJC1; HOXB7; NPM1; FOXF1; CREM; RAN; IRF4; PRMT2; BATF; EGR3; YWHAB; BHLHE41; BCL11B; TBL1XR1; MYCL; TBL1X; ASCL1; ELF3; BMI1; CREB3; ATF4; RBM14; TSC22D1; BRPF1; NR2F1; CD3D; INSM1; OLIG2; SOX10; SMARCE1; CHD3; KLF2; NCOA4; KLF6; ZNF302; ZNF217; ZHX2; NKX2-2; FOXG1; ABL1; HMGB2; EDF1; FOXC1; CITED2; ZNF711; POU4F1; TOX3; HDAC1; SP140L; BASP1; BRD3; HDAC2; ZBTB18; ATF3; ADNP; CITED1; BRD8; MED1; KDM5B; ZMYM2; NONO; MAGED1; KDM5D; TLE4
Down-regulation	80	ZMIZ1; ZNF195; MAFB; PMS1; ZNF44; ERBB4; WWTR1; RBBP8; TFDP2; ZNF669; IRF9; ZFP36L1; MTF2; NFE2L1; JUP; ZNF423; C1QBP; SIAH2; ZNF165; ETS2; MED21; ZNF136; ZNF611; CHD9; PRKDC; BBX; NCOR2; CERS4; POU5F1B; TCEA1; TRPS1; PBXIP1; TRIM22; HOXC4; ZNF665; ZBED2; RYBP; THAP10; FOXN3; ZNF430; RBM39; ESR1; YAP1; KLF11; PSIP1; ZNF160; WT1; TFEB; ZNF331; RORA; TEAD4; KLF10; ZBTB38; PRRX1; ZFP36L2; IRF8; ETS1; PCBD1; ZNF432; HMGA1; NFIB; HLX; PBX3; EMX2; ID1; PAWR; SOX17; CEBPB; HDAC9; TXNIP; NR1H2; ZNF721; TWIST1; HES1; ZNF91; MYBL1; MEIS1; MEF2C; GATA6; IRF6