Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID23436	Motesanib	GSE70138	NEU	Human	24h	3.33uM	EID0049

Response Information :

Types	Number	Response transcription factors
Up-regulation	116	ZNF586; NFAT5; ZNF419; SMAD1; USP16; ZBED1; ZNF148; TXNIP; SFMBT1; ZNF587; ZIC1; MED12; ZNF134; ZNF551; NCOR2; ZNF606; FLNA; PAXBP1; PPARGC1A; ZBTB43; TSC22D2; MGA; ZBTB38; ZNF304; NFATC3; ZNF468; NKX2-2; JUND; SIM2; ZNF665; ZNF432; PBRM1; LHX2; CREB5; MED13; ING3; BRD8; ENO1; SETD2; WHSC1; ZNF43; MED1; PKNOX1; ZNF91; OLIG2; NCOA4; HMGB3; RBPJ; ZSCAN18; HEY1; ABL1; NR1D2; YWHAB; CARM1; ZNF430; TCF20; HEY2; KDM5D; ADNP; MSX1; TCF4; TRAK1; ZNF160; NUP62; ZNF711; ZNF264; RORA; RAN; RBM14; NEDD8; RHOA; CHD7; HDAC2; MTF2; ZNF24; TCF12; PSPC1; MXI1; ATF4; ZNF292; ZNF266; KDM5A; DPF2; BRD3; NFIB; ARID4A; TCERG1; LEF1; ZNF721; ASCL1; REPIN1; RLF; SATB1; TCEB2; SMARCC1; ZMIZ1; PURA; FUBP1; EDF1; KDM5B; ZMYM2; TLE1; TOX3; MECOM; ZEB2; PHF20; ARID4B; DDX17; SMARCA4; NONO; RBBP4; MAGED1; ZMYND8; HSF2; NRIP1; BASP1
Down-regulation	115	RBPMS; WT1; SSBP2; MEIS2; HAND1; MED21; LIN28A; JAK2; OSR2; GATA4; ZIC3; KDM4C; HHEX; AR; LMCD1; FOXL2; CREB3; SUPT3H; MAFB; PAX9; EHF; NR4A2; YAP1; BNC2; CREBL2; GATA6; ELK3; TGFB1I1; KLF11; MNDA; TRIM22; THAP10; LYL1; IRF2; HOXD3; MAFF; NANOG; ZFPM2; HOXB2; PRDM14; WNT4; GRHL2; NFE2L3; PNRC1; CBX7; SPDEF; NR0B1; SOX17; TAF4B; SKIL; TRIM16; AGO2; CREM; CEBPB; MYNN; TEAD4; PGR; NR4A1; ESR1; TCF21; FOSB; PBX1; TDP2; PITX1; SUB1; MED14; TULP3; PHOX2B; TFEC; SRCAP; PCBD1; ZBED2; CDK2; ZNF215; ZBTB16; MYRF; SP140L; BNC1; E2F8; RFX5; POLR3C; ZNF394; TTF2; VDR; ISL1; HDAC9; ZHX2; CD3D; STAT6; PSIP1; PSMC3; TFAP2C; ETS1; KLF10; IFI16; NR1H2; ERBB4; POU2AF1; NFE2L2; ACTL6A; WWC1; CCNH; CEBPD; IRF8; IRF6; SNAI2; HES1; ATF3; GATA2; HOXB6; TRIP6; TFAP2A; MEIS1; TRIB3; PPARG