Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID23435	Motesanib	GSE70138	NEU	Human	24h	10uM	EID0049

Response Information :

Types	Number	Response transcription factors
Up-regulation	138	PPARG; NR3C1; FOXF1; SATB2; CDK8; RRN3; MSX1; BPTF; EP400; HMG20A; ALX1; CDYL; CARHSP1; RAN; NRBF2; TAF4; LEF1; CAMTA1; ADNP; ZEB2; YWHAB; TLE4; ERBB2; ZNF711; ATF2; ID3; TXNIP; BAZ2B; BRD8; ID4; ID1; RBPJ; RNF10; ATF4; PBRM1; ZNF536; NFYC; RFC1; ZNF248; MED13; NCOA6; UBE2I; ZNF302; SETD2; ZNF131; GTF2IRD1; TCF12; TAF1D; KLF5; PURA; MKL2; ZKSCAN7; TSC22D2; HSBP1; SMARCA5; CHD7; ZNF292; ZNF266; ZNF146; AFF1; PHF20; NCOA1; CHD9; ARID4A; SPEN; CHD1; PUF60; FOXO1; JARID2; SIAH2; SATB1; EYA1; RCOR1; INSM1; RLF; ZIC1; CREB5; LPIN2; HDAC2; BRPF1; MEOX2; SMARCA1; MYT1L; PATZ1; BTF3; VPS72; SMARCC1; ZEB1; HMGB3; CTR9; TCERG1; KAT6A; PRKDC; RHOA; ETS2; TBX3; ZMYND8; TOX3; HSF2; TBL1X; NR1D2; DACH1; RBBP4; BMI1; DNMT3B; VGLL4; TCEB2; NONO; HEY1; BASP1; FOXJ3; SOX2; KDM5B; RFX5; ZMIZ1; NUP62; MTF2; ZMYM2; PBX1; HDAC4; FOXF2; SSBP2; DDX5; KAT6B; SMARCA4; PCGF2; IRF8; PSIP1; BRD3; MAGED1; HLTF; ZNF721; SMARCD3; MYCN; MED1; MECOM; NRIP1; KDM5D
Down-regulation	93	MAFB; TFAP2C; ZNF444; ZBED2; GRHL2; SNAPC4; ZNF544; ZNF331; PSMC3; ZSCAN18; RNF138; LIN28A; KLF6; SOX17; ERBB4; AR; CDC5L; HOXB2; EGR1; FOSB; FOXM1; PBX3; ZNF415; TTF2; SOX13; BHLHE41; IRF3; CDK9; TFEC; ELF5; BNC1; CCNH; TGFB1; SPDEF; HDAC9; PCBD1; RBPMS; EHF; PGR; E2F4; NKX2-1; LOXL2; HTATIP2; PPP1R13L; IRF6; ATN1; ZNF239; NR4A2; NR5A2; MBD2; NR0B1; SOX18; WWC1; ATF3; FOXE1; HMGA1; KLF9; ZBTB16; CDK2; TRPS1; E2F8; OVOL2; ACTL6A; CALR; HHEX; ESR1; NFKB2; RBBP8; ZFP36L2; WT1; ERG; JUP; VDR; ELK3; EMX2; TEAD4; TRIM22; AEBP1; STAT6; PAWR; KLF2; ARID5B; NR1H2; CITED2; HES1; HOXB6; NFE2L2; ZNF394; GATA2; TFAP2A; TRIB3; GATA3; NFATC3