Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID23397	Ibrutinib	GSE70138	NEU	Human	24h	0.12uM	EID0049

Response Information :

Types	Number	Response transcription factors
Up-regulation	103	STAT3; MLX; MAFG; ZNF266; SREBF1; TSC22D2; AFF1; EGR3; CREBZF; CREG1; THRAP3; SALL2; MGA; PBX3; PLAGL1; IRX5; ZNF32; PHIP; ZNF146; BCL11B; SMARCA1; TAF1D; RXRA; TOX; ZNF512B; ZFP64; HMBOX1; MED6; PQBP1; CHD8; RUNX3; ZNF783; PURA; ZNF292; JARID2; CHD3; PBX1; GLI3; ABL1; KDM2A; FOXG1; TRRAP; MYT1L; NONO; ZNF43; PEG3; IRF7; PBRM1; NEDD8; ID2; VPS72; INSM1; RBBP4; CHD7; HSF2; SCAND1; ZNF302; SMARCA5; HDAC4; HMGN3; SMARCD3; BAZ2B; FOXJ3; FOXO3; MED1; FUBP1; PUF60; ATF4; MTF2; NCOA1; YWHAB; CTR9; NCOA4; PCGF2; DNMT3B; SOX2; HDAC2; HLTF; ZNF721; SIX1; TBL1X; ADNP; NKX2-2; MAGED1; MYB; ZMYM2; TCERG1; BASP1; BRD3; NUP62; LEF1; ZNF160; ZMIZ1; KDM5B; SSBP2; ERG; ZNF91; CARHSP1; SMARCA4; CITED1; ZBTB18; NRIP1; TOX3
Down-regulation	81	TFCP2L1; KLF5; MYBL1; MYCL; SOX9; IRF1; MED21; RNF138; JAK2; ELF5; HOXB5; FOXD1; TFAP2A; TLE2; TRIM29; JUN; MEOX1; HMGB1; HOXB7; CNOT3; SNAI2; ELF3; RBBP8; TP63; JUP; HOXB6; MBD2; CDX1; EN1; CALR; HOXC4; LOXL2; CREB3; CCDC59; HOXB2; GFI1B; MEOX2; YEATS4; WWP1; NFE2L2; KLF9; KLF2; EGR1; BHLHE41; SLC2A4RG; SUB1; POLR3C; ATN1; SRCAP; STAT6; PA2G4; PIR; NR0B1; BCL3; FOXM1; ACTL6A; VDR; HES1; PTRF; TEAD4; CDK2; PAWR; HOXD1; MECOM; FOXF2; IRF6; HHEX; TGFB1I1; KLF13; CCNH; PSIP1; E2F8; TRIM22; ZNF394; TRPS1; AEBP1; GATA2; TGFB1; ID1; TRIB3; ATF3