Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID23396	Ibrutinib	GSE70138	NEU	Human	24h	0.37uM	EID0049

Response Information :

Types	Number	Response transcription factors
Up-regulation	100	SATB2; SAP18; ZFP69B; LZTS1; RLF; TADA3; MSX1; EYA2; NPM1; ZNF337; ZNF529; TOX; IKBKAP; MYCL; HMBOX1; COPS2; CTBP1; PURA; BBX; LHX2; CAMTA1; NKX2-2; ZNF91; CREB3L1; NFYC; RBPJ; NR3C2; SMARCA2; KLF5; HLF; TRIM24; MYT1L; HDAC1; ZEB2; POU3F2; VPS72; SALL1; TXNIP; ING3; NR1H2; ZMYND8; YWHAB; ZIC1; HEY1; REPIN1; RBM14; TRIM29; SMAD5; TSC22D1; BAZ2B; RUNX3; ZNF711; TLE4; CARM1; HSF2; INSM1; ZNF292; HSBP1; SPEN; EDF1; BTF3; ZNF146; TCERG1; UBE2I; RFX7; NUP62; HDAC2; ZNF131; CHD8; BCLAF1; NEDD8; ZNF189; CTR9; KAT7; HEY2; SMARCD3; MED23; DPF2; KDM5B; KDM5D; HMGN3; NONO; SOX2; DNMT3B; LEF1; MEIS1; MED1; ZMYM2; HLTF; BASP1; RBBP4; TBL1X; BCL11B; KAT6B; PSIP1; SMARCA4; BMI1; JARID2; NRIP1; MAGED1
Down-regulation	70	ZMIZ1; HMGA2; CDYL; TGIF1; MYRF; FLNA; GATA6; ZNF215; ZNF423; ELK3; RBPMS; VDR; EGR1; ZBED2; ERBB4; ZFPM2; ZNF239; MEOX1; STAT1; ZBTB16; SOX9; SERTAD2; MKL2; HOXD3; RBBP8; NFE2L2; CREB3; WWTR1; RUVBL1; KLF9; IRF9; ERG; PRRX1; NR2F6; IRF8; HHEX; ESR1; LMCD1; WWP1; HMGA1; ACTL6A; WWC1; NFE2L3; HOXB2; AEBP1; BNC1; MAFB; KLF11; HLX; KLF13; MYBL2; CCNH; CDK2; TWIST1; MBD2; PAWR; TEAD4; TFAP2C; DACH1; TCF21; HDAC9; HES1; GATA2; IRF6; TRIB3; SNAI2; TFAP2A; MYBL1; NFATC3; ATF3