Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID23395	Ibrutinib	GSE70138	NEU	Human	24h	1.11uM	EID0049

Response Information :

Types	Number	Response transcription factors
Up-regulation	162	RBL2; MXI1; PBX3; ZNF32; MGA; TAF12; ZBTB14; ZNF44; ELF2; IRX5; ZNF148; CREG1; RNF10; ZNF3; HMBOX1; ZIC1; ZBTB1; ZBTB43; MAFG; NFATC3; CREBZF; DNMT3B; UBE2B; GTF2A2; TXNIP; ZEB2; ZMYND8; TFDP2; POU2F1; CDK8; FLNA; RNF4; RCOR3; CASZ1; MSX1; ZNF23; ZNF84; ZNF443; RBPJ; RORA; YWHAB; PURA; EP400; ZFP64; SERTAD2; ZNF268; HIC2; TRIM32; PIAS1; IKBKAP; MEIS1; MEF2A; SMAD5; CTBP2; HDAC2; CCNE1; MYCN; RAN; POU5F1B; NR1D2; ZNF510; ING3; NPM1; PPARGC1A; MLLT10; CHD8; EDF1; TAF7; LPIN2; BPTF; BRD8; CBX3; ABL1; TULP4; HDAC6; PCGF3; KDM2A; NFAT5; ZBTB38; BRD3; GATAD2A; SPEN; YAP1; KDM5A; PAX5; BRPF1; TCERG1; EZH2; BTF3; WHSC1; HSF2; MAGED1; RFX7; NCOA4; SIX1; HNRNPD; PSPC1; SSBP2; VPS72; TBPL1; SETD2; ZNF131; SATB2; MNT; NONO; ADNP; RBBP4; SMARCE1; KMT2A; KDM5B; RHOA; KAT6A; MED23; SMARCD3; ZNF160; PCGF2; HMGB3; MYT1L; CHD7; PHF20; HTATIP2; RERE; TRAK1; SOX2; SMAD1; ID1; E2F5; NUP62; ZNF711; PIAS2; PBX1; BCL11B; ZBTB18; EMX2; KAT7; SMARCA5; JARID2; ZMIZ1; FUBP1; SMARCA4; ZMYM2; EYA1; HLTF; TLE1; CITED2; FOXJ3; ZNF292; DDX5; ZNF721; SMARCC1; BAZ2B; TCF4; SATB1; PSIP1; TOX3; MTF2; NRIP1; BASP1; CITED1; KDM5D; KAT6B; TBL1X
Down-regulation	163	MTA1; PUF60; IL16; HSF1; SOX13; CBX4; C1D; JUP; ENY2; NR2F6; THRA; NKX3-2; ZBED2; FOXB1; SMARCB1; TLX3; RBPMS; SCRT1; NPAS2; PSMC3; SUB1; TP73; IRX4; TBX1; TFAP2C; SOX9; POU1F1; CAPN15; NR5A2; POU4F3; SUPT3H; ATN1; MLLT1; AES; TAF1C; RFXANK; CDC5L; MTDH; SREBF2; IRF2; ZNF667; CALR; ZNF580; ZNF362; JUN; LMCD1; TLE2; REL; SOX14; CNOT3; SPI1; BNC1; FHL2; ASCL2; VDR; FLI1; TCF21; TGFB1I1; NEUROG2; ETS2; GBX2; ZNF674; CHD2; SOX18; YEATS4; POLR3C; ELF1; SRY; TBX5; BHLHE41; EHF; POU2F3; CDYL; CDK9; HOXD1; ZNF695; ZNF623; ELF3; ZHX2; SOX17; CAMTA2; ZNF551; FOXI1; ZFPM2; EMX1; TRIM22; VGLL1; SPDEF; SIX3; MNDA; OVOL2; FOXF1; TRIM16; ZNF134; CDX1; SOX10; PPP1R13L; ARID4B; FOXE1; ST18; SLC2A4RG; ZNF331; TRIP11; CDK2; MYNN; IRF1; KLF13; AEBP1; GFI1B; POU4F1; RUNX1; MYBL2; ZNF512B; LOXL2; NFKB2; PTRF; CEBPB; ZNF557; HMGA1; HDAC9; RAD21; MYCL; RUVBL1; SNAI2; NFE2L2; SKIL; PITX1; TRPS1; PCBD1; ACTL6A; NR1H4; NFATC4; GATA6; TCF7L1; HLX; HHEX; TBX3; IRF6; IRF9; TRIP6; TTF2; SP100; TFAP2A; NR1H2; FOXF2; WT1; E2F8; CCNH; CRYM; IFI16; CEBPD; ARID5B; TP63; NR2F1; TGFB1; FOXM1; NR4A2; ERG; TRIB3; MBD2; ATF3; HES1; GATA2