Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID23394	Ibrutinib	GSE70138	NEU	Human	24h	3.33uM	EID0049

Response Information :

Types	Number	Response transcription factors
Up-regulation	94	CCNA2; GTF2IRD1; NR2F2; PEG3; ERBB2; ZEB2; TBX3; IRX5; CAMTA1; TLE4; RYBP; ZKSCAN7; MAFB; FOXO4; ZNF711; BRD8; ZNF3; RNF10; BTF3; NHLH2; MYT1L; SMAD6; NPM1; TULP4; SMAD1; ID2; PUF60; ISL1; PLAGL1; CBX3; FOSL2; MNT; EYA1; DNMT3B; ATF4; ERBB4; MYCN; GATA3; INSM1; ZNF131; NKX2-2; RHOA; ZNF43; NONO; GLI3; RAN; SMARCE1; RFX7; RBPJ; TOX; JARID2; KDM5D; VPS72; ZNF91; PCGF2; ZFHX4; TOX3; DACH1; EDF1; PBX1; CHD8; CITED2; TCF4; MEIS1; NUP62; SOX2; HDAC2; BAZ2B; MTF2; RBM14; NCOA4; BASP1; CTR9; ZMIZ1; RBBP4; KDM5B; SSBP2; SMARCC1; TSC22D1; CARHSP1; BMI1; ZMYM2; ADNP; MED1; SMARCD3; DDX17; ZMYND8; HSF2; KAT6B; BRD3; TBL1X; MAGED1; SMARCA4; NRIP1
Down-regulation	63	THAP11; ATF6; MAK; TLE2; GCFC2; FOXJ1; KAT2B; SHOX2; ETV4; JUN; NKX2-1; JAK2; MAFF; KLF9; PSMC3; BARX1; RREB1; ATN1; FOXN3; REL; E2F8; ACTL6A; HMGA1; MYBL1; NFE2L3; ATF3; TTF2; PIR; GATA6; SOX17; CDK2; VGLL4; IRF6; VDR; RUVBL1; EMX2; LOXL2; HHEX; EHF; KLF4; SP140L; SRCAP; JUNB; PSIP1; ZNF557; CEBPD; ZBED2; CCNH; ZNF394; SLC2A4RG; HES1; HEY1; NR1H2; CALR; SOX9; NR4A2; HDAC9; HOXB7; ESR1; ZBTB16; TGFB1; AEBP1; NFATC3