Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID23393	Ibrutinib	GSE70138	NEU	Human	24h	10uM	EID0049

Response Information :

Types	Number	Response transcription factors
Up-regulation	119	PPARG; MZF1; SAP18; GATA4; SREBF1; PKNOX1; NCOR1; MEN1; CREB3L1; TAF1D; ZNF692; ZEB2; NCOA6; CTBP2; POLR2A; ZBTB18; KMT2A; FOXO4; BATF3; ARID1A; STAT5B; PHIP; HIC2; ERBB2; MXI1; PAXBP1; NR2C1; SIX2; UBE2I; ZNF292; NCOA1; PCGF2; ZIC1; ZNF587; JARID2; ZNF146; EYA1; ZNF432; NR2F2; MYCN; SATB2; ZNF721; RNF4; TCF20; RERE; BRPF1; HDAC6; HDAC1; FOXO3; ZMYND8; INSR; RYBP; ZNF160; INSM1; SOX2; TBX3; SPEN; MYRF; KDM2A; PBRM1; ZNF423; PSPC1; ZNF430; ZNF302; PUF60; DPF2; ZNF711; HSF2; RFX5; ADNP; ZNF131; PURA; ZNF266; SETD2; KAT7; CHD8; BRD8; PQBP1; TOX3; MTF2; KDM5B; NEDD8; HDAC4; BAZ2B; HOXB7; ZNF189; MNDA; MYB; RLF; CHD7; ZMYM2; BASP1; ARID4B; RBBP4; ZMIZ1; PATZ1; TULP4; BMI1; SMARCD3; PEG3; YWHAB; CITED1; BRD3; SMARCC1; SMARCA5; HEY1; FOXJ3; KAT6B; SATB1; NUP62; RBPJ; HDAC2; MED1; SMARCA4; TBL1X; ASCL1; NRIP1; TLE4; MAGED1
Down-regulation	84	ELK3; ARL2BP; CDC5L; HMGB1; JUN; GTF3A; PRRX1; TGFB1I1; SMAD1; MAFB; TRIB3; NAB2; SOX17; TAL1; SPIB; CBFB; LOXL2; ANKRD1; ZFP36L2; NR0B1; BNC1; IRF6; ERG; WNT4; EGR4; SKIL; FOXI1; ELF5; RNF6; HDAC9; MBD2; KLF9; TULP3; NR0B2; CREB3; ZBED2; PDLIM1; FOXM1; TDP2; SRCAP; DLX5; WWTR1; SMAD7; WT1; ESR1; PCBD1; PTTG1; ATF3; HOXB2; EGR1; ACTL6A; STAT4; ID3; SOX18; OVOL2; DLX2; MYBL2; SLC2A4RG; NFE2L2; EMX2; KLF11; E2F8; NFIB; PAWR; POU4F1; ARID5B; NR4A1; NR4A2; PSIP1; CDK2; KLF13; TEAD4; TRIM22; CCNH; STAT6; ZBTB16; HES1; ZFPM2; KDM5D; TGFB1; GATA2; TFAP2A; GATA6; MYBL1