Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID23373 Gdc-0068 GSE70138 NEU Human 24h 0.12uM EID0049
Types Number Response transcription factors
Up-regulation 146 ZNF83; ZNF586; PROX1; ZNF573; RCOR1; CHD9; ZNF43; ZNF587; EYA1; CREB3L1; MAML1; ZIC3; NCOR2; ZIC1; ZNF415; ZNF273; NPM1; NCOA1; SAP18; ZNF468; ZNF443; MNDA; DNMT3B; MSX1; TAF7; JARID2; ZMYND8; NRBF2; LEF1; BCOR; MNT; ZNF84; ZEB2; DEAF1; TOX; ZNF93; NFE2; ZNF529; NEUROD1; ZNF266; PURA; GATA2; ZNF516; ZKSCAN7; CHD3; SIX2; ZNF91; CREB5; TRIM24; SMARCA1; BRPF1; BCL6; ZNF134; SP110; TSC22D1; PBX3; ZNF331; CREG1; TRIM32; NEDD8; CUX2; MAF; RUNX3; PAX6; MAGED1; MYT1; ARID4A; ZNF302; RFX7; DACH1; LPIN2; ZNF423; TLE1; ZNF32; HDAC4; DDX17; ZFHX4; TCF12; INSM1; ZNF711; ZNF432; RREB1; BRD8; TXNIP; TBPL1; DDX5; ZNF292; MYCN; NONO; YWHAB; SMARCC1; EGR3; KAT6A; BAZ2B; PBX1; SMARCD3; BTF3; ZSCAN18; PIAS2; CHD7; ZMYM2; HEY1; ZNF189; HLTF; ISL1; TRAK1; ZNF160; EDF1; RBPJ; NKX2-2; KAT7; SOX2; SATB1; MYT1L; ABL1; SOX9; BASP1; NUP62; ZNF131; MTF2; KDM5B; ZMIZ1; MECOM; HDAC2; BCLAF1; VGLL4; FOXJ3; ZNF721; PHF20; PEG3; ADNP; PCGF2; BRD3; HSF2; ARID4B; ZBTB18; BCL11B; MEIS1; RBBP4; TOX3; TBL1X; KAT6B; SMARCA4; ASCL1; NRIP1; MED1
Down-regulation 81 SPEN; GRHL2; CREB3; ZBED2; ARL2BP; PTRF; WNT4; IRF1; PRDM12; MKL2; OVOL2; YBX3; SRCAP; TFAP2A; TERF2; VGLL1; CREB1; PSMC3; HOXB2; POU2AF1; EGR1; ZNF215; ELK3; ZBTB16; ID3; RBPMS; IRF4; JUP; CD3D; NFE2L2; FOXE1; ARNTL2; PCBD1; TCF3; VDR; SHOX2; NR5A2; BNC1; ETS2; IRF8; ATF3; CCNH; TGFB1I1; SP140L; HHEX; PIR; ZNF557; BHLHE41; NKX2-1; OSR2; FOXO1; JUNB; E2F8; ZFPM2; CREB3L2; NR4A1; TP63; IRF6; RUVBL1; HOXB6; HTATIP2; TCF21; NFIB; CBX7; EPAS1; SLC2A4RG; LITAF; ACTL6A; AEBP1; WWC1; PSIP1; HIRA; BACH2; CDK2; MBD2; AHR; HLX; NR1H2; TRIB3; GATA6; ESR1