Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID23368 Bosutinib GSE70138 NEU Human 24h 0.04uM EID0049
Types Number Response transcription factors
Up-regulation 48 CREB1; HOXA5; SPDEF; TP53; LYL1; SOX10; CREBL2; SALL1; LMCD1; ZNF222; HMGB2; ZHX2; RBPMS; CITED2; CEBPG; TULP3; SOX17; LOXL2; SKIL; HHEX; KLF2; TEAD4; EMX2; NR1H4; MYBL1; ZNF331; FOSB; HOXB7; ERBB4; GATA6; STAT1; ELF3; CD3D; BCL3; MECOM; PITX1; TRIM22; ZNF652; CALR; TGFB1I1; NFE2L3; TOB1; STAT6; TWIST1; HOXB2; ESR1; TRIB3; PSIP1
Down-regulation 56 ZKSCAN1; TBL1XR1; RCOR1; MAFB; HMG20A; TRRAP; ID3; KLF5; EGR3; IRF4; MYB; PCGF3; RFX5; KMT2A; CHD1; ZNF248; IKBKAP; HMBOX1; DACH1; HDAC4; ZFHX4; REPIN1; ZNF532; HIVEP2; SATB1; FOXJ3; EYA1; ZEB1; TCF4; SFPQ; ZNF432; HMGB3; DDX5; ZNF292; TBX3; FUBP1; HLTF; HDAC2; IRF8; BMI1; TXNIP; ZNF160; CHD7; MYCN; RBPJ; ADNP; MAGED1; POU2AF1; ZBTB18; ZBED2; ZIC1; TLE4; TOX3; SMARCA4; ID1; BASP1