Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID23364	Bosutinib	GSE70138	NEU	Human	24h	3.33uM	EID0049

Response Information :

Types	Number	Response transcription factors
Up-regulation	110	TP53; KLF3; EPAS1; PPARG; ZNF224; BLZF1; COPS5; AFF4; GFI1; SOX21; TLX3; TDRD3; CDK7; FOXD1; CSDC2; ZFY; ZNF529; TBX10; ERG; SSX3; RRN3; NR5A2; JAK2; IFNB1; POU4F3; PTRF; ZNF652; CD3D; ZNF426; MYF6; FOXA2; STAT4; TBX1; SOX14; ZXDB; TMF1; FHL5; ID1; XBP1; TP73; SUPT3H; CREM; HOXD10; PITX1; BCL11B; CREB3L1; FLI1; TAL1; GATA4; REL; ARNTL2; SMAD1; HIPK3; CREBL2; MAFF; TCEA1; POU4F1; ELK4; SLC2A4RG; NR0B2; DAXX; RUNX3; SIX2; KLF6; ZNF552; NR1D2; WWP1; VGLL1; MECOM; MYBL1; IRF1; KDM5D; CEBPG; TEAD4; NFE2L3; KLF5; CEBPB; HHEX; IRF7; INSM1; SOX18; NR1H2; CBX7; STAT1; HOXB13; ZNF33B; ELF4; EMX2; NR1H3; MYRF; PDLIM1; TWIST1; HOXC10; JUNB; ZBTB20; SOX17; PAWR; GTF2I; KLF9; SNAI2; NR4A2; CEBPD; ASCL1; TGFB1I1; TGFB1; TCF21; GATA6; MED1; TOX3; TRIB3
Down-regulation	82	ATF7IP; AR; BRD4; PUF60; NFIC; ZKSCAN1; ZNF22; ZNF415; NFAT5; PBX3; ILF2; CNOT2; ZBTB1; HMGB1; FOXF1; SSBP2; REST; SERTAD2; MEIS1; SF1; SALL1; ZNF432; NAB2; TFAP2C; SKI; CHD4; KLF10; RCOR1; SOX10; CERS4; HSBP1; POU5F1B; ZNF536; PAX6; PAX5; ZNF562; DACH1; RORA; BCLAF1; LOXL2; RBM39; KAT2B; CHD9; CUX1; DMTF1; SUB1; EGR2; POU2AF1; MNT; RBM14; BAZ2B; EGR3; ISL1; CTBP2; HTATIP2; CREB3L2; SMARCA5; RERE; ZNF331; BRD8; TULP4; SOX9; TLE4; PIAS2; BASP1; BTG1; YWHAB; STAT6; MSX1; MYB; CCNH; TXNIP; HLTF; RBBP8; SMARCD3; CRYM; NFATC3; MAGED1; RBBP4; MEF2C; BMI1; ZBTB18