Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID23316	Idelalisib	GSE70138	MNEU.E	Human	24h	3.33uM	EID0048

Response Information :

Types	Number	Response transcription factors
Up-regulation	110	BRCA1; NFATC4; ETS1; PPARD; HMG20B; CREG1; ELF2; SIAH2; ZNF76; PCBD1; HOXB2; GLI3; IRF6; HOXA11; TAF6; TGFB1I1; TFDP1; BACH2; SIX6; RXRB; AR; RFX7; MED21; HBP1; KAT8; CUX1; TRRAP; FOXO1; ZNF212; MED24; PBXIP1; TXNIP; MYCL; KLF5; FOXA1; TFEB; RING1; TTF2; NFAT5; KAT5; PLAG1; NR3C2; YBX3; HLX; SND1; NELFB; EMX2; RSF1; TRIM32; PCGF2; WT1; MAFF; EHMT2; OSR2; WWTR1; TLE2; RUVBL2; ARID5A; NR4A3; SHOX2; PLAGL1; PGR; RBL2; CBX7; LEF1; BAZ2B; CCNT1; TEAD3; SMAD1; MEOX2; E2F8; TOX3; ELF5; DDX17; TCF7L1; NR5A2; ZFP36L1; RBFOX2; ZNF91; RLF; RARB; HEY2; PAX6; TCF4; YAP1; MDM2; JUP; MLXIP; CREB3L1; ESR1; MAF; HOXB6; TBX21; SMARCA1; SLC2A4RG; BNC2; MAFB; RXRA; EGR3; IKBKAP; POU2AF1; RBPMS; IRF8; RERE; PITX1; NKX3-1; TBL1X; FLI1; MAGED1; ZIC1
Down-regulation	70	WWC1; TBPL1; DNMT1; MTA1; BHLHE41; HNRNPD; CBX3; PHIP; KAT6B; USP22; SMARCC1; YWHAB; CBFB; SNW1; RBM39; ENY2; HMGN3; RNF138; CCNH; ZNF24; RAN; CCNC; FUBP1; ZNF532; SP100; SP110; ZNF195; TCF20; DACH1; TOB1; ARNT2; MTF2; SFPQ; CEBPG; NCOA6; ETV5; E2F3; BMI1; CHD7; NPM1; ZFP36L2; TAF10; CSDE1; RUNX1; TAF1A; CEBPB; SP140; TCEA1; MYCN; TBL1XR1; ZNF165; HSBP1; CNBP; SNAI2; ZBTB1; RNF14; ATF3; AHR; FOSB; TFAP2A; ZFPM2; TRIM24; ZNF423; DMTF1; TOX; DDIT3; SOX9; LMCD1; ID3; TWIST1