Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID23296 Osimertinib GSE70138 MNEU.E Human 24h 0.04uM EID0048
Types Number Response transcription factors
Up-regulation 19 ZIC3; CRYM; MYB; MNDA; CREB3L2; VDR; SIAH2; TRPS1; TRIB3; CITED2; ARNT2; TCF4; ESR1; SOX11; RBPMS; MYBL1; TFAP2A; FOXF2; PBX1
Down-regulation 19 PDLIM1; HNRNPD; NR1D2; PHF20; YWHAB; ZBTB38; KDM5D; MDM2; ASCL1; NKX2-2; MAFB; HTATIP2; WWTR1; AFF1; AHR; HOXB7; AEBP1; BCL11B; MAGED1