Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID23292	Osimertinib	GSE70138	MNEU.E	Human	24h	3.33uM	EID0048

Response Information :

Types	Number	Response transcription factors
Up-regulation	53	KDM5A; NCOA4; KLF4; RAN; SMARCA1; HOXB2; GLI3; TBL1X; MITF; JARID2; HOXB7; WWTR1; MXI1; CREB1; PTTG1; CITED2; TCF7L2; ZNF281; TRIP6; TGIF1; HMGN3; NR2F1; CBX5; SSX1; NFATC1; DEK; ENO1; KLF9; TRIM22; AHR; BTG1; MAGED1; MED1; PURA; STAT6; CENPF; MAF; ID3; HOXB6; ZFPM2; CREB3L2; ERBB2; CD3D; ZBTB38; RXRA; HTATIP2; EPAS1; MAFB; ZIC1; KDM5D; PBX1; BCL11B; MEIS1
Down-regulation	38	STAT1; IRF9; BMI1; ZBED2; SREBF1; COPS2; DNAJC1; CAMTA1; NFE2L1; TCF12; ITGB3BP; JUNB; SUB1; MNDA; BRIP1; PRKDC; CERS6; CRYM; ZNF423; RBBP8; INSR; TOX3; SMAD7; MEIS2; ERBB4; ZNF551; IRF7; MYRF; BHLHE41; LMCD1; GTF3A; SATB2; INSM1; FOXG1; DLX2; TWIST1; ESR1; TRIB3