Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID23189 Tivozanib GSE70138 MNEU.E Human 24h 0.37uM EID0048
Types Number Response transcription factors
Up-regulation 38 ZBTB20; ORC2; NR3C2; MYB; BAZ2B; PROX1; LYL1; NFE2; BHLHE41; POU2AF1; MECOM; TAL1; ZSCAN18; MYRF; DACH1; ZNF423; ERBB4; HOXD1; KLF2; HIRA; BCL11A; SSX1; DLX2; EGR2; TLE4; INSM1; ZMYND8; ZEB2; ZFPM2; TWIST1; ST18; MNDA; NFIB; PEG3; TRIP6; KLF9; EMX2; ESR1
Down-regulation 20 FOXJ3; UBE3A; HNRNPD; ADNP; ZNF91; TAF1D; BATF; APEX1; AES; FOXD1; SPIB; SMAD1; ATF4; TGFB1I1; NR2F1; TBX21; ZBTB16; KDM5D; CD3D; RUNX3