Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID23179	Mitoxantrone	GSE70138	MNEU.E	Human	24h	10uM	EID0048

Response Information :

Types	Number	Response transcription factors
Up-regulation	183	SOX2; NFATC4; MYCBP; GMNN; SOX13; PPARG; FOXD1; GATA2; MED14; TRIP11; KLF5; HIRA; E2F4; NANOG; SPDEF; HLX; CDK2; ZNF771; SMARCD2; ZNF235; HMGB2; SNAI2; PTRF; PRDM14; ZNF816; VGLL1; FOXE1; SLC2A4RG; TWIST1; TCEA1; MEIS2; FOXM1; AGO2; HOXD9; HOXA11; TFDP3; MYBL1; MED15; HMGA1; CDX2; ZXDC; TCF7L1; IRF3; IRF9; ENY2; TGIF1; TCF21; CNOT3; BNC1; FOXH1; ZNF500; CDYL; SIM2; NR1I3; EMX1; ZBTB16; TP73; POLR3C; OVOL1; ZNF239; LIN28A; ZNF350; CEBPB; TTF2; CCNE1; KAT2B; PPP1R13L; ZNF667; THRB; FHL2; PNRC1; NFKB1; PTTG1; NR0B1; OSR2; MBD2; HOXD10; HOXD11; TFAP2C; WT1; SKIL; TGFB1; TFAP2A; GRHL2; HOXA10; ZNF623; NR5A2; DEK; FLNA; PRRX1; TGFB1I1; RCOR1; NAB2; MYCL; BNC2; RUVBL1; LHX3; SOHLH2; HMG20B; MYNN; ACTL6A; YAP1; KDM4C; SRCAP; FOXL2; WWTR1; ZNF215; RARG; YEATS4; DLX2; HIVEP1; ELK3; ARID5B; ZHX2; THAP10; FOXA1; TRIM22; CAPN15; RAD21; PAX9; HSF1; E4F1; PITX2; PBX3; FOXG1; NFIC; EP300; GFI1B; ZNF7; FOXO1; TEAD3; TGIF2; TP63; TLE2; PGR; NFE2L2; VDR; TRPS1; C1QBP; NFE2L3; ZNF217; TRIM16; NR1H2; GATA6; ESR1; AEBP1; JUP; SMAD6; NR1H3; ZNF551; CENPF; FOXF2; SSX1; ZBED2; AR; CREB3L2; PDLIM1; TEAD4; ZNF580; LMCD1; WNT4; SATB2; DNMT1; EMX2; TRIM24; CALR; YBX3; DLX5; CITED2; E2F2; ARNT2; ZFPM2; NKX2-1; RBPMS; TBX3; TRIP6; TRIB3; HOXB2; RORA; SHOX2; TOB1; TRIM29; DACH1
Down-regulation	153	HOXA5; MTF2; ZNF721; USP22; MYT1L; ZNF24; CAMTA1; SOX4; CHD9; NFIL3; ZMIZ1; SPEN; PARP1; ZNF160; TSC22D2; MYT1; HDAC2; PCGF2; SMARCA5; NCOA6; RBPJ; MED24; NEDD8; HIVEP2; FOXO3; TRAK1; DPF2; NLK; RBBP4; SSRP1; MED1; PHF20; CDK7; APEX1; ID2; NRIP1; MYC; TCERG1; HSF2; FOXJ3; SMARCD3; PHIP; ZMYM2; SOX11; CTBP1; MED23; HMGN3; BRD8; RERE; TULP4; ECD; SMARCA4; HSBP1; PURA; CHD8; CCNH; ZNF711; ZNF91; DEAF1; MAGED1; ZBTB38; ZNF292; PPARGC1A; BCLAF1; ING3; SCAND1; BRPF1; ZNF248; ZNF14; DRAP1; PEX14; SP110; IRX5; CSDE1; HNRNPD; SETD2; USF2; TXNIP; SMARCC2; BRD3; KAT7; CRY1; COPS2; ASCL1; TAF1D; TCF12; ZNF432; MYCN; KLF10; TCEB2; NCOR2; NCOA4; SMARCE1; ZNF146; TCF25; ZNF226; IRF8; ABL1; YWHAB; BMI1; MSX1; NAB1; ZKSCAN7; PIAS1; ADNP; EDF1; RYBP; SFPQ; POLR2A; BAZ2B; PQBP1; ZMYND8; HTATIP2; NFAT5; ZNF302; CARM1; RBFOX2; SUB1; HLTF; ISL1; NCOA1; ZBTB18; ZNF43; BBX; HMBOX1; ZNF423; PAX5; EGR2; RUNX3; MED6; DNMT3B; ZNF117; TBL1XR1; BHLHE41; TSC22D1; TCF4; HOXC6; CERS6; HDAC6; ETS2; TLE1; BATF3; HIPK3; ZNF22; ZEB2; SAP30; RXRA; KLF6; DMTF1; BTG1; SOX9; IKBKAP; CREB1