Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID23169 Nvp-bgj398 GSE70138 MNEU.E Human 24h 1.11uM EID0047
Types Number Response transcription factors
Up-regulation 55 IKBKAP; ZBTB38; JARID2; SMAD7; NR4A1; DNMT3B; RBPMS; ABL1; HMG20B; EWSR1; POLR2A; MAGED1; NCOA2; TGFB1I1; TCERG1; ZNF160; MKL2; MNT; STAT6; ZBTB16; AFF1; CBX7; ARID4B; HDAC4; TRIM32; ZNF721; VGLL4; MSX1; MLXIP; HMGN3; SIAH2; IRF2; SMARCD3; PURA; PLAG1; KDM5D; RYBP; SHOX2; MAF; HMBOX1; ISL1; CREB3L1; MYCN; BATF3; NCOR2; FOXO1; ZSCAN18; ZBTB18; PEG3; SMARCA1; SMAD1; ZMIZ1; TOB1; ESR1; TXNIP
Down-regulation 60 SOX10; TAF12; ARNT2; MBD2; HSBP1; DMTF1; TFAP2A; SP100; ZNF32; DLX4; CDK2; SMARCD2; ZBED2; ENO1; AHR; ERF; PROX1; SOX9; THAP7; SUMO1; BCL6; ZNF227; TAF1A; ZNF165; CREB3; TEAD4; PAWR; CEBPG; ZNF195; HOXD3; KLF4; SIX3; NR2F6; HMGB2; ID2; PPP1R13L; NEUROD1; HTATIP2; GFI1; NPAS2; EHF; DLX2; CARHSP1; YBX3; NR1H3; KLF9; HIRA; TFAP2C; WWC1; GATA6; RAN; FOXL2; NR5A2; TRIB3; NFE2L3; NPM1; EPAS1; MYBL1; DACH1; BHLHE41