Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID23036 Cgp-60474 GSE70138 MNEU.E Human 24h 10uM EID0047
Types Number Response transcription factors
Up-regulation 142 GATA3; NFATC4; CCNA2; LZTR1; FOXD1; NR0B2; MBD4; NAB2; NHLH1; BRWD1; MED15; HIF3A; IRF3; KDM4C; THAP7; DLX2; SUPT3H; CDK2; EN1; TWIST1; PROP1; VGLL1; MYCL; TBX19; MZF1; AHR; ZXDC; PHF1; WWTR1; SLC2A4RG; ZNF74; SSX3; HOXC4; HMGB2; ZNF816; SPDEF; PAX6; FUBP1; TAF12; MYBL2; LIN28A; TFAP2A; MBD2; RUVBL1; TEAD4; ZNF266; MXD4; TGFB1; SNAI2; SATB2; TRPS1; HOXC11; NR2F1; KAT2A; BNC1; PPP1R13L; HDAC9; NFX1; ZBED2; EHF; ZKSCAN8; MEIS2; MAFF; TGIF2; SOX13; HOXC10; SMARCD2; ZNF211; AFF4; NR1H3; ARID5B; ZNF224; KLF11; ELK4; IRF9; CREBZF; EPAS1; PHOX2B; TGFB1I1; PNRC1; FOXC1; RBL2; GMNN; DLX5; SMAD6; PRRX1; ZEB1; TBX2; TTF2; MYBL1; EYA1; LOXL2; CBX7; SKIL; ESR1; ID3; RAD21; IRF6; JUP; GATA2; TCF21; HOXB2; ZNF83; ID1; BTAF1; KLF9; TP63; ST18; JUNB; PTRF; SOX17; HOXA11; FOXF2; ELK3; NR2F2; PDLIM1; NR4A2; ARNT2; ZSCAN18; TXNIP; HMGA1; NANOG; SHOX2; PEG3; TRIB3; EMX2; YAP1; TULP3; PLAGL1; NR0B1; CD3D; TOB1; NR1H2; INSM1; TAF10; HEY1; OSR2; TFAP2C; NFE2L3; ELF5; WT1; BHLHE41
Down-regulation 133 SOX4; NFIL3; ABL1; TBPL1; FOXO3; USP22; GTF2A2; PRDM4; SCAND1; HDAC2; SFPQ; JARID2; NRIP1; SMARCD3; ING3; CDK7; NUP62; UBE2I; PBRM1; ATF6; ZMYM2; NKX3-1; TCERG1; ZFP64; SMAD2; MYC; ID2; HIF1A; BIRC2; SMARCC1; AFF1; ECD; INSR; NLK; ARID4B; CTCF; MED13; MAGED1; CHD8; ZNF146; KAT7; UBP1; NCOA6; NFE2; RBM14; RERE; IKBKAP; CERS6; CTR9; SUB1; DPF2; RREB1; CREB5; ADNP; TRIM32; TERF2; BRD8; RUNX1; RBBP4; ZBTB38; BRD3; MED27; ZBTB18; REPIN1; KMT2A; MAX; TSC22D2; RBPJ; TBL1XR1; ASCL1; CARM1; PHF20; ZNF302; CITED1; NRBF2; CNOT2; HNRNPD; ZBED1; ZNF721; TFAM; RYBP; RNF10; MED1; BCLAF1; ZNF160; KDM5D; PPARGC1A; MYT1; RUNX3; CTBP2; MYB; NR2F6; SPEN; ZNF24; ZEB2; DNMT3B; LPIN2; HOXA5; SMARCA4; ZMIZ1; CRY1; CUX2; ZNF22; GATAD2A; JUND; YWHAB; HMGB3; ATF4; ASH2L; E2F3; EGR2; SIAH2; HIVEP2; HLTF; HOXB7; KLF10; APEX1; NR3C2; NCOR2; CREB1; BATF3; ZFPM2; FOXO1; MYT1L; TLE1; TBL1X; RAN; POU2AF1; ARID1A; ZMYND8; SMAD1; PUF60; ETS2