Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID23017	Mitoxantrone	GSE70138	MNEU.E	Human	24h	10uM	EID0047

Response Information :

Types	Number	Response transcription factors
Up-regulation	108	MYCBP; HMGB2; HLX; ZNF586; ZNF544; MBD2; SLC2A4RG; CDYL; ZNF350; SPDEF; TDP2; TFAP2A; FOXD1; ZNF239; VGLL1; TGFB1; RUVBL1; PTTG1; WWTR1; FOXM1; POLR3C; TRIP6; ERG; BNC2; CCNE1; ZSCAN31; MYBL2; SNAI2; ZNF419; RUNX1; LYL1; ZNF816; HDAC9; CREB3; MYBL1; MXD4; TFDP2; CDK2; NR3C1; AEBP1; ZHX2; TCEA1; DLX2; ZNF175; TRPS1; AHR; GMNN; YBX3; RAD21; CENPF; ZNF394; IRF9; DEK; PPP1R13L; HMGA1; SMARCD2; TBX2; ENY2; HBP1; MNDA; TFEC; LOXL2; ZBED2; ZNF580; NR1H3; SIM2; TLE4; EMX2; CREBL2; PNRC1; ZNF217; ACTL6A; MYCL; SOX13; AGO2; FOXF2; ST18; TTF2; DNMT1; TFAP2C; DLX5; TWIST1; TOB1; IRF7; DACH1; ARNT2; PDLIM1; LMCD1; ELK3; FOXA1; TRIM29; NR1H2; AR; CREB3L2; PTRF; JUP; VDR; TGIF1; WT1; MAF; FLNA; ESR1; ERBB2; CD3D; TRIB3; KLF2; TRIM16; STAT4
Down-regulation	124	NFIL3; HDAC6; SOX4; USP22; IKBKAP; TCERG1; RBPJ; FOXO3; FOXJ3; ABL1; TBPL1; TSC22D3; RERE; ZBED4; PARP1; MTF2; NRIP1; MED24; ZNF721; PHF2; TCF20; ZMYM2; REPIN1; SMARCD3; ZNF160; CHD8; MYT1L; NCOA6; UBE2I; DPF2; PCGF2; SMARCE1; DNMT3B; RBBP4; ZBTB18; ZBTB38; CARM1; CDK7; KAT7; BIRC2; BCL6; SALL2; E2F6; MAGED1; SCAND1; HSF2; PHF20; ZNF131; MAX; PQBP1; MED1; ING3; ISL1; MYC; TAF1D; E2F5; RUNX3; ZNF267; CNOT2; RBFOX2; ZMYND8; NFAT5; TULP4; PSPC1; HOXA5; BTG1; SMAD2; NLK; KLF7; ASCL1; HMG20A; PPARGC1A; MED6; BRPF1; INSR; SUB1; STAT6; MNT; ZNF24; TCF12; YWHAB; MYT1; BRD3; HOXC6; PITX1; PIAS1; ADNP; CAMTA1; MYCN; JUN; SOX9; SMARCA4; ZNF423; ATF4; NR3C2; HOXD1; SMARCC2; SOX11; HDAC4; TXNIP; HLF; CSDE1; RYBP; BATF3; CHD9; NCOR2; ELF3; DMTF1; CARHSP1; CUX2; CREB1; TBL1XR1; PAX5; APEX1; TCEB2; KLF10; EGR3; POU2AF1; ZMIZ1; BCL3; TOX3; ETS2; DEAF1; TLE1