Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID22970	Osimertinib	GSE70138	MNEU.E	Human	24h	1.11uM	EID0046

Response Information :

Types	Number	Response transcription factors
Up-regulation	55	GATA2; FOSL2; WDHD1; RBL1; ZNF202; INSR; PSMC3IP; PHF20; TFEC; BLM; IFI16; TEAD1; ISL1; PITX2; CERS6; ST18; HEY2; ZEB2; ZNF528; TWIST1; MYB; PFDN5; NEUROD1; ASCL1; HOXD1; SAP30; WT1; NFE2; HOXB6; MAFB; FOXN3; FLI1; HOXB7; NKX2-2; MYCN; TLE4; MECOM; HOXB2; JARID2; ZNF423; ZNF32; ZBTB18; HIPK3; ZFP36L2; ELK3; ESR1; TFAP2C; MEIS1; ADRB2; HLF; LEF1; AHR; MNDA; TXNIP; HOXA5
Down-regulation	33	CRK; UBE2I; PQBP1; HDAC6; MXD4; RFXANK; SPIB; JUNB; RBBP7; MAF; PAWR; SOX9; TCF7; LPIN2; PAX5; TCF7L1; ZNF160; TGIF1; TCF21; IRF4; TBL1X; LITAF; HEY1; TCF4; CDYL; HMGA1; SATB2; CBX6; KAT2B; YBX3; BTG1; POU2AF1; TRIB3