Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID22692	Vorinostat	GSE70138	HUES3	Human	24h	10uM	EID0042

Response Information :

Types	Number	Response transcription factors
Up-regulation	321	CEBPA; PPARD; EGR1; SOX4; ADRB2; JUN; IRF9; ASCL3; ID2; SPDEF; CEBPD; MYBL1; ZNF224; MEIS2; NFE2L2; GATA2; NR4A3; NEUROG1; EVX1; STAT4; SNAI2; BARX1; PSMD9; CDK2; HOXD1; CREM; NR5A1; KAT2A; HSF4; ZNF331; PAX8; RING1; PRDM12; BRD4; KLF6; MEF2D; ARID5A; SIN3B; SP140L; STAT1; ZBTB17; LHX3; GBX1; SP100; NFKB2; SNAPC4; NOC2L; ZNF611; CBX4; ZNF91; ZFHX4; SIRT2; ZNF507; IRF7; SIRT7; MAML3; ACTL6B; HOXB1; PRDM2; CHD2; TRIB3; SUPT5H; MED31; TWIST1; FOXF2; SUPT7L; SPI1; HCFC2; CALCOCO1; EMX1; REL; L3MBTL1; E2F4; RBPJL; MITF; MAK; ZBED2; BANP; ALX3; MBD2; LZTR1; IKZF2; ZSCAN9; THRB; ZNF500; SERTAD2; ZNF235; TULP2; NR6A1; ZNF44; CRX; CDIP1; SP110; NR1I3; ZXDC; GATA1; SIX5; ZNF557; PROP1; TAF1C; TGFB1; VENTX; SCRT1; DOT1L; ZNF688; TCEA2; EN1; ZNF239; ETV2; TAF6L; HOXC5; ONECUT1; ZNF771; RXRB; CBX7; DLX2; HIF3A; DACH1; NFKBIB; ZNF335; HMGXB3; ZNF701; TSHZ2; ZNF136; PPP1R13L; ZNF440; ZNF362; OSR2; PAX1; NR2E1; CREB3L2; PIAS4; MYC; ERBB4; ESRRG; POU2AF1; RORC; BNC2; STAT2; HOXA4; TP73; TFAP2A; BHLHE41; SOX9; ZNF350; CREB3; RBBP5; PTRF; TLX3; NOCT; RUNX3; ZNF180; SKIL; ATOH1; SAFB2; ZEB1; IRF1; ST18; IRF5; PRDM10; ZNF778; TBR1; AFF4; ZNF257; PLAGL1; RFX1; ZKSCAN4; NR0B2; PPARA; CSDC2; HOXA3; EMX2; TEAD3; SIX1; ZNF10; KDM4C; PRDM1; ZNF407; POU4F3; ZNF814; ZNF81; TBX21; HMX1; ZNF780B; VDR; MEOX2; ZNF225; BNC1; ZNF562; HLX; FEZF2; E4F1; MED15; VGLL1; CXXC1; TBX1; TAF4B; CEBPE; KLF5; MXI1; MLLT1; ZNF155; HOXD11; POU2F3; MYT1; ISL1; NR2F1; SUPT4H1; ZNF215; CRYM; ZNF692; FOXG1; LYL1; BRDT; ZNF682; TULP3; ARNT2; SUPT6H; MNX1; BRD2; LDB1; KLF2; ZFPM2; NHLH2; ZNF576; ANKRD1; ZNF573; NR4A2; HDAC9; PHF1; ZNF324; MECOM; SOX18; CAMTA1; DLX5; IRF6; EYA2; ZNF536; ZNF345; SHOX2; ZNF654; CREB5; THAP10; SP140; ZNF160; SOX13; HBP1; ZBTB20; ZNF394; TCF7; CREBL2; RORA; ZBTB7A; HEY1; WT1; NFIC; ESR1; ZNF117; NEUROD1; TP63; TDP2; PRPF6; JUP; ZNF264; FOXJ1; ELF4; BAZ2A; ETV5; ARID5B; RXRG; NR4A1; SMARCA2; ZNF205; TOB1; SOX17; ATF3; NR1H4; HOXC10; JAK2; INSM1; WNT4; FOXA2; TFEC; ZKSCAN1; FOSL2; PCGF1; AEBP1; FLI1; PITX1; HMG20B; ELF3; BTG1; DAXX; SIX3; CITED2; TBX2; ZNF232; PRRX1; PAWR; CTBP2; BCL3; FOS; ZNF512B; HHEX; MYRF; EPAS1; TCF21; KAT2B; HOXB2; NFE2; TRIM29; PEG3; ZNF721; TRPS1; MNDA; EYA1; LITAF; PAX5; IRF8; ZIC1; GATA6
Down-regulation	237	HMGA2; ATF1; ZMYM2; CCNA2; PSIP1; TP53; HDAC2; FOXJ3; DMTF1; TCERG1; PCBD1; ZFP64; ADNP; SMARCA4; PATZ1; NUP62; SMARCE1; RBBP4; DEK; ETV1; NFKBIA; DPF2; ARID4B; RFX5; PMF1; BRD3; SNW1; ZNF532; HMGB3; XBP1; FHL2; RHOA; RBM14; SMARCA5; BCLAF1; ZNF274; LIN28A; HNRNPD; AFF1; REST; ORC2; GABPB1; ZNF672; POU5F1B; SP3; SALL2; CBX5; DNMT3B; KAT8; MTA1; CARHSP1; SAP30; RFX7; ERBB2; SPEN; BASP1; TRIM32; CREBZF; VEZF1; ELK1; SIAH2; PCGF2; CDK7; ING2; HLTF; SMAD4; MYCN; JARID2; HDGF; CTCF; NONO; RAN; ZNF589; NPM1; KAT7; HMGB2; TBL1XR1; ZNF84; CNBP; NACA; TBL1X; HTATIP2; ZNF813; WDHD1; ARID4A; ZBTB1; ENO1; HSBP1; ZNF614; NPAT; UBP1; EP400; USP22; RNF138; NCOR1; MED6; HSF2; ZNF292; NFE2L1; NANOG; ZMYND11; CNOT1; SETD2; ZNF24; PLAGL2; MAGED1; PIAS3; STAT5B; MED4; UBE2I; WHSC1; HMG20A; TCF12; TCFL5; TRIM24; ZNF629; RFC1; PIAS2; PHF2; BAZ1B; TRRAP; ZNF134; BATF; TRAK1; SMARCD1; NCOA4; CTBP1; BCL11A; DDX17; EDF1; MGA; BCOR; BATF3; ATF4; NCOR2; MAX; MKL2; SATB1; MLLT10; FOXO3; PLAG1; DDX5; PMS1; IRF2; ZBTB14; CENPF; MAZ; REPIN1; SFPQ; NCOA1; AGO2; ASH2L; STAT6; FOXO1; BMI1; ZNF146; APEX1; CBX3; BTAF1; GTF2I; IRX5; ZIC3; ECD; ZNF189; STAT3; SSRP1; SREBF2; KDM5B; CHD7; ZNF516; GTF2IRD1; E2F6; NFYB; HDAC1; USP21; ZFX; MED1; ZEB2; TFDP2; NCOA6; TRIM28; KAT6B; CRY1; RNF4; TULP4; YEATS4; MYB; SMAD2; BAZ1A; PDLIM1; ZNF217; CCDC59; PTTG1; HMGB1; NEDD8; MEF2A; SMAD5; BLM; PURA; DEAF1; BTF3; ZNF22; E2F5; TGIF1; EGR3; C1QBP; ATF5; YBX1; RBPJ; ZBTB16; CHD9; NAB1; ITGB3BP; NKX3-1; NR1D2; RBBP7; TAL1; ZNF107; ZSCAN18; LEF1; RBPMS; NFATC1; SALL1; RERE; KLF10; SOX11; YWHAB; KLF9; TSC22D1; HOXC6; TFAP2C; SUV39H1; NR2F2; ASCL1; KDM5D; ID1; SSBP2