Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID22534 Nvp-bgj398 GSE70138 HUES3 Human 24h 10uM EID0040
Types Number Response transcription factors
Up-regulation 112 RELB; GATA3; FOXO4; ID2; SUPT7L; MBD4; UBE2B; NFATC4; ZMIZ1; BCL3; PSMD9; ZNF532; TFAP2A; CREM; ZNF410; HOXC10; ZNF112; USP21; DNAJC1; ZNF492; RARA; ZNF304; TRPS1; CXXC1; HIVEP1; INSM1; BCL11B; ZNF606; HDAC9; BIRC2; HDAC4; BCOR; ESR1; SKIL; HOXC4; ZNF354A; PGR; ZNF222; BMI1; TFAP2C; UBE2I; HMBOX1; ARL2BP; SOX11; HDGF; ZNF32; DLX5; TLE4; TCF4; AR; ZNF432; THAP1; EHF; ZNF711; ZNF444; ZBED4; ZNF516; SIX3; ZNF45; ATF7IP; RARG; HOXD3; GTF3A; SREBF1; SFPQ; CALR; ZFP36L2; BRD4; PHOX2B; SPIB; IRF9; TWIST1; LMCD1; HOXA1; ZNF467; TCF7; NHLH2; PBX1; ZNF239; WT1; SALL2; GATA2; ERBB4; ZHX2; ISL1; SALL1; BAZ2B; IRX5; SMAD6; MYRF; CNOT3; ZNF423; JUP; HIC2; TCF12; CBFA2T3; ZNF331; TOX; NR0B1; FOXG1; ARNT2; VDR; ABL1; JARID2; EMX2; MYB; TOX3; TSC22D1; MYBL1; SOX9; MAFB; HOXC6
Down-regulation 62 MYC; RFX5; TP53; ETV1; SUZ12; TCFL5; CCNA2; ZNF652; PBX3; ETV4; WWTR1; YBX3; ZIC1; BATF3; ETS2; TCF21; RAN; PTTG1; HLTF; ZKSCAN1; HMGB2; CCNC; PTRF; NOC2L; HLF; SMARCA5; NPM1; FOXC1; MLXIP; RBL2; KDM5D; ERBB2; BHLHE40; ELK3; TCF7L2; NFE2L1; MED1; NKX2-1; IRF1; FOXF1; ZNF274; PIR; RBPMS; ENO1; CRYM; MYCL; NKX3-1; ID3; DNMT3B; ATF3; LEF1; BHLHE41; ZFP36L1; ZNF91; POU2AF1; HMGB3; KLF2; TXNIP; TRIM29; FOSL1; ID4; PPARG