Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID22525 Idelalisib GSE70138 HUES3 Human 24h 0.37uM EID0040
Types Number Response transcription factors
Up-regulation 80 CREB5; DMRT1; IRF9; ZNF362; HOXD3; ZNF606; TFEC; NFE2; SKIL; NFE2L3; NR1H4; WWC1; CTBP2; NKRF; ZSCAN31; CREB3; ZNF175; ZBED2; BAZ2B; THAP10; ZBTB20; PROX1; DAXX; ZSCAN16; HMGN3; GATA6; ANKRD1; POU4F2; BRWD1; HOXD1; SRY; MYRF; KLF1; ZNF544; ZNF217; ARNT2; ZNF354A; CAMTA1; ZNF83; GTF3A; ZNF267; ELF4; E2F8; POLR3C; HDAC9; ARID4B; ESR1; NEUROD1; ZNF239; DLX5; TFAP2A; HIRA; TULP3; MEOX1; EHF; TLE4; LYL1; ERG; WT1; MAFB; TAL1; NFE2L2; DACH1; NPAS2; SMAD1; ARID5B; AHR; ZFPM2; INSM1; NR4A2; TRPS1; TRIM22; EN1; ASCL1; MECOM; MYBL1; ST18; ZNF423; ZHX2; EMX2
Down-regulation 28 THAP11; PUF60; KAT7; EYA2; MAGED1; ING2; TFAM; MTA1; CREB3L1; BHLHE40; PIR; STAT5B; RORA; RBBP4; ZNF652; ZKSCAN1; HMGA1; TGFB1I1; SOX10; RBPMS; BTG1; SATB2; MXI1; HEY1; FOSB; LEF1; FLNA; TXNIP